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Record No. 3480
Record ID 003480
Publication type Journal Article
Title Prevalence Of Rh And ABO Blood Groups In HIV Seropositive Pregnant Women In Enugu, Nigeria
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Nneli, R.; Ekpo, B.; Ohaeri, O.
Journal Title Nigerian Journal of Physiological Sciences
ISSN 0794-859X
Date of publication 2004
Volume and n° 19(1&2)
Pages 7-9
Language English
Descriptor Rhesus genes; Pregnant women; Prevalence; HIV seropositive
Abstract HIV status and blood groups determination (Rhesus and ABO groups) in 3691 pregnant women attending antenatal clinic at a Mission Hospital and Maternity and 1199 non-pregnant women visiting the same institution for marriage-related matters, or blood donation, or out-patient department between 1999 - 2002 were studied. Blood sample from each subject was screened for HIV using the quick test kits and tested for blood group types with anti-sera A, B, AB, and D. Overall, the prevalence of blood group O+ was higher than in the general population with highest rate of 62.9 in HIV+ pregnant women followed by 58.4 in HIV- pregnant women and 58.0 in non-pregnant women. No difference was observed in groups A+, B+, AB+, O- for the three categories of subjects studied. Blood groups B-, AB- were conspicuously absent in HIV+ pregnant women but non-significant in HIV- pregnant women and the control. A- was very few in all the categories. Rh -ve accounted for 3.16 (HIV+), 3.46(HIV-) and 2.67 (Control) while Rh +ve were 96.84(HIV+), 96.06 (HIV-) and 97.33(Control). Thus, the higher than normal prevalence of group O+ in HIV+ pregnant women is indicative of the population size for this group. The very low prevalence of Rh -ve in type A- suggests that incompatibility could be higher than in this population and protective in HIV infection contrary to the previous report in apparently healthy population. The obvious absence of Rh- in AB group suggests that AB may have a higher percentage of protection against immunization. Hence in group B, less incidence of Rh incompatibility and haemolytic disease of the young in the mothers in blood group AB will occur.


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Record No. 3479
Record ID 003479
Publication type Journal Article
Title Haematoxic Effects Following Ingestion Of Nigerian Crude Oil And Crude Oil Polluted Shellfish By Rats
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Eyong, E.; Umoh, I.; Ebong, P.; Eteng, M.; Antai, A. B.; Akpa, A. O.
Journal Title Nigerian Journal of Physiological Sciences
ISSN 0794-859X
Date of publication 2004
Volume and n° 19(1&2)
Pages 1-6
Language English
Descriptor Haematological Indices; Crude Oil; Shellfish
Abstract The haematological effects following ingestion of shellfish exposed to crude oil polluted water or the pollutant perse were investigated in albino Wistar rats. Feeding of four groups of rats for 28 days duration with two reference casein or shellfish protein control diets (Group A and B), and two test diets (Group C and D) supplemented at varying levels with shellfish which had been previously exposed to crude oil polluted water and the oral gavaging with crude oil at the rate of 3, 6 and 9 ml/kg body weight per day to three groups (groups II, III and IV respectively) of rats for 7 days duration resulted in changes in packed cell volume (PCV), red blood cell (RBC) and white blood cell (WBC) counts, and haemoglobin concentration (Hb) of rats. Group C and D respectively fed 10 and 20 polluted shellfish diets recorded significant (P 0.05) decreases in PCV and RBC counts while Hb concentration and WBC counts increased. Groups II, III and IV gavaged with varying doses of crude oil recorded significant (P 0.05 - 0.01) dose dependent decrease in PCV and RBC counts when compared to controls (group 1). Hb and WBC counts also increased for these groups but the increase was only significant for WBC counts (P 0.05) when compared with controls. The results suggest that the ingestion of shellfish exposed to crude oil polluted water or the polluted perse results in haematotoxicity.



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