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Record No. 11305
Record ID 011305
Publication type Journal Article
Title A Review of Immunisation Policy and the African Child
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Omoleke, I. I.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Place of Publication Lagos
Publisher College of Medicine of the University of Lagos, Department of Physiology
Date of publication 2009
Volume and n° 8(2)
Pages SP
Language English
Descriptor Immunization; Health Policy; Child; Review
Descriptor-Geographic Africa
Abstract Background: This paper set out to review immunization policy in African States using Nigerian experience with a view to identifying policy failure (if any). It attempted to highlight the shortcomings and the impact of the immunization programme/policy on African Child. The paper proffered solutions. Methods: The paper utilized both primary and secondary sources of data but heavily depended on secondary source. The study used descriptive and inferential statistical methods to analyse the information gathered. Results: The findings of the study revealed that, although immunization policy has achieved tremendous impact on African child by reducing to some extent, the killer diseases attacking African child, yet the immunization coverage is relatively low (Tables I-IV), when compared with the European nations. Conclusion: It concluded that implementation of immunization policy is weak and underfunded. It therefore recommended that public enlightenment and awareness of the policy be stepped up adding that African governments should back up the policy with adequate funding and effective political will if only for the sake of innocent African child.


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Record No. 11304
Record ID 011304
Publication type Journal Article
Title A Study of Factors Influencing Brain Drain among Medical Personnel in Nigeria
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Adetayo, J. O.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Place of Publication Lagos
Publisher College of Medicine of the University of Lagos, Department of Physiology
Date of publication 2010
Volume and n° 9(1)
Pages 19-29
Language English; English
Descriptor Emigration and Immigration; Health Personnel; Socioeconomic Factors
Descriptor-Geographic Nigeria
Abstract The economic depression of the late 80's has made work force groups particularly in the medical industry to look beyond their nose and seek for greener pasture somewhere outside their environ at all cost. This economic situation deeply affected the medical groups that migration became the chorus of the medical personnel. This perennial situation made the study to examine the factors influencing brain drain among the medical personnel in Nigeria, using a selected University Teaching Hospital Complex as a case study. A protested 5-point Likert scale questionnaire was administered to 85 randomly and purposively selected medical personnel, to ferret the causes of immigration and the corresponding effect on the provision of medical services and development of future medical personnel in the country. The survey made use of both historical and descriptive research methods. The survey was based on the light of high skilled personnel popularly referred to as brain drain. The data gathered through the questionnaire were subjected to simple descriptive statistical analysis. The results were ranked in the order of importance. The result showed that migration decision is mainly caused by the conditions within the organization rather than the pull factors. The motivation of workers is at very low level, with ability to meet the physiological needs rated first with 30.6 percent of the respondents strongly agreed to this concept. The effect of brain drain was also significant on the provision of medical services, training and development of future medical personnel. The result depicted that the push factors are the most important influences in the decision to migrate than the pull factors. The survey revealed that desire for better life could be counted as the most important factor for searching for greener pasture (75.0 percent) considering pull factors; better working condition was considered as the very important reason for migration (87.0 percent) migration. The migration of medical personnel would endanger the development of future medical personnel. It was concluded that desire for better life is the most important factor as the basis for the migration decisions, and certainly brain drain is the fall-out of economic depression. If this syndrome is not addressed promptly it will continue to hinder the development and delivery of medical services in this country.


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Record No. 11303
Record ID 011303
Publication type Journal Article
Title Dental Spacing in Primary Dentition of Nigerian Children and its Relationship to Arch and Crown Dimensions
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Yemitan, T. A.; Dacosta, O. O.; Sanu, O. O.; Isiekwe, M. C.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Place of Publication Lagos
Publisher College of Medicine of the University of Lagos, Department of Physiology
Date of publication 2010
Volume and n° 9(1)
Pages 30-36, fig., tab.
Language English
Descriptor Dentition, Primary; Dental Arch; Crowns; Child
Abstract Objectives: The aims of this study were to compare mesiodistal and buccolingual crown widths, as well as dental arch dimensions between children with spaced and normal dental arches; and to determine which of the parameters mostly influence dental spacing. Methods: Crown and dental arch dimensions of dental casts of 125 children, grouped into spaced and normal primary dental arches, based on the tooth size-arch length discrepancy, were measured using electronic digital caliper. The data were statistically analyzed using t-test and stepwise multiple regression analysis. Results: Maxillary and mandibular spaced arches had statistically significant larger intercanine widths than the normal arches. The total mesiodistal tooth size in both arches, and mean buccolingual width of the mandibular first and second primary molars of the spaced arches were significantly smaller than those of the normal arches. However, there were no significant differences between spaced and normal arches in arch length, arch depth and intermolar arch width. The most important predictor of spacing in both arches is the intercanine width, followed by total mesiodistal tooth size. Conclusions: The parameter that mostly influences dental spacing is the intercanine width.


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Record No. 11302
Record ID 011302
Publication type Journal Article
Title Swollen Forearm in an 11 Year Old Nigerian Boy
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Akinola, R. A.; Olayiwola, B.; Bankole, M. A.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Place of Publication Lagos
Publisher College of Medicine of the University of Lagos, Department of Physiology
Date of publication 2010
Volume and n° 9(1)
Pages 15-18, fig.
Language English
Descriptor Forearm; Vascular Malformations; Phlebography; Angiography
Descriptor-Geographic Nigeria
Abstract The diagnostic challenges in an 11 year old boy with a swollen forearm in a resource limited country, Nigeria, is discussed, with a brief review of literature of the causes of forearm swelling in a child and vascular malformations. This case is presented because of the rarity of arteriovenous malformation and the difficulty in making a diagnosis due to its low level of suspicion as a differential diagnosis. In this country where there is paucity of vascular surgeons, the challenges of management of arteriovenous malformations and the various imaging modalities are discussed.


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Record No. 11301
Record ID 011301
Publication type Journal Article
Title Urea and Creatinine Clearances in the Three Trimesters of Pregnancy
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Eiya, B. O.; Obika, F. O.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Place of Publication Lagos
Publisher College of Medicine of the University of Lagos, Department of Physiology
Date of publication 2010
Volume and n° 9(1)
Pages 10-14, fig., tab.
Language English
Descriptor Urea; Creatinine; Pregnancy Trimester, Third
Descriptor-Geographic Nigeria
Abstract The aim of this study was to determine the creatinine and urea clearances, as indices of glomerular filtration rate (GFR) during the three trimesters of pregnancy. A total of 108 healthy subjects between the ages of 18 and 37years were divided into non-pregnant women (28+5years, n=30), 1st trimester of pregnancy (28+5years, n=18), 2nd trimester of pregnancy (28+4years, n=30). Serum and urine samples were collected at mid-trimester period. Creatinine and urea concentrations in serum and urine were determined using Jaffe's method for creatinine and the urease (Ccr) and urea clearance (Uurea) in the three trimesters when compared with the non-pregnancy value. The increase in creatinine clearance peaked in the second trimester (64.76+1.37 (non-pregnancy vs. 2nd trimester), while the increases of 34.50+3.68ml/min (non-pregnancy vs. 1st trimester), and 38.63+1.56 (nonpregnancy vs. 3rd trimester) were similar. These increases in Ccr were associated with a significant fall (p0.01) in all trimesters of pregnancy. Il is conclued that GFR increases in pregnancy until term, with a peak at the seond trimester


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Record No. 8578
Record ID 008578
Publication type Journal Article
Title Periodontal Status of Adolescents in Surulere, Lagos State, Nigeria
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Umesi Koleso, D. C.; Ayanbadejo, P. O.; Savage, K. O.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6(1)
Pages 88-92
Language English
Descriptor Periodontal Diseases-prevention and control; Periodontal Diseases-diagnosis; Periodontal Diseases-therapy; Adolescent
Descriptor-Geographic Nigeria
Abstract Objective : The objective of this study was to assess the periodontal status, treatment needs and dental visit practice of adolescents in Lagos, Nigeria. Methods : 600 subjects were selected by stratified random sampling from 6 schools, 3 secondary and 3 primary schools in Surulere Local Government Area of Lagos state, Nigeria. About one hundred subjects in each age category of 11 to 16 years were selected. A questionnaire was designed seeking biographic data such as age, sex, occupation of parent, and dental visit attendance and a section for recording periodontal clinical examination using the Community Periodontal Index of Treatment Needs (CPITN) was included. The periodontal status, treatment needs and dental visit practices of adolescents were determined. Results: Only 3 were found to be healthy periodontally. 83 of the subjects presented predominately with the worst condition recorded, code 2 (i.e. calculus), which is a reversible condition. A mean of 0.6 healthy sextants, 2.3 bleeding sextants and 3.1 calculus-accumulated sextants was calculated. A statistical difference in periodontal status was noted with age, the younger adolescents (11-13 years) presenting predominately with bleeding sextants when compared to the older adolescents (14-16 years) who presented more calculus-accumulated sextants. Nearly all subjects required periodontal treatment. 83 needed professional prophylaxis (TN2). Conclusion: There is a need for a school oral health education programme within the LGA with a focus on periodontal disease prevention and provision of oral prophylaxis by dental surgeons, therapists and volunteer dental students.


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Record No. 8577
Record ID 008577
Publication type Journal Article
Title Gender Differences related to HIV/AIDS in South West Nigeria
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Uti, O. G.; Sofola, O. O.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6(1)
Pages 83-87
Language English
Descriptor Gender Identity; HIV; Acquired Immunodeficiency Syndrome; Disclosure
Descriptor-Geographic Nigeria
Abstract The aim of this study was to determine some underlying gender differences in the pattern of infection in a group of HIV positive patients in Nigeria. It involved 328 consecutive HIV positive patients attending dedicated clinics at four teaching hospitals in the South western part of Nigeria. Information on patients' socio-demographic characteristics and their attitude towards disclosure of their HIV status were collected with an interviewer administered questionnaire. There was a significant difference in the age distribution between the genders with a higher proportion of those younger than 35 years being females and higher proportion of males in the older age groups (p 0.05). A higher proportion of the female respondents were unemployed (73.2), students (88.9) and small scale traders (62.5) compared to the males. There was also a significant difference between the genders concerning disclosure of HIV status with the males more willing to disclose their status compared to the females (p 0.05). Fear of breach of confidentiality and discrimination were the most common reasons given. Conclusion: There is a need for economic empowerment of women as poverty increases the vulnerability of women to the infection.


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Record No. 8576
Record ID 008576
Publication type Journal Article
Title The Prevalence of Oral Habits Among 4 to 15 year Old School Children in Lagos
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Quashie-Williams, R.; Dacosta, O. O.; Isiekwe, M. C.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6(1)
Pages 78-82
Language English
Descriptor Habits; Prevalence; Child; Schools
Descriptor-Geographic Nigeria
Abstract Objective: To provide information regarding the prevalence of oral habits among a group of Nigerian children. Study Design : This is cross-sectional study of 928 children, 431 males and 497 females aged 4 to 15 years from both rural and urban areas of Lagos State in Nigeria. Habits assessed included digit, lip and tongue habits. Results: Thirty four point one per cent of the children examined presented with an oral habit. Of these, digit sucking was the most frequently occurring, seen in 50 of the children with oral habits. Tongue and lip habits occurred in 27 and 23 of children respectively. There was observed a steady decrease in oral habits with an increase in age. The prevalence being highest among 4 to 5 year olds (44.2) and gradually decreasing to 11.8 among the 14 to 15 year age group. Oral habits were found to be slightly more common among males than females, though this finding was not significant. Socio-economic status (SES) was found to have a significant effect on the occurrence of oral habits. Forty eight per cent of all children of high SES engaged in an oral habit, whereas this was observed in only 24.4of all children of low SES. Conclusion : The findings of this study indicate that there is an increased prevalence of oral habits among children in the population in recent times. The occurrence of these habits is more frequently seen in children from families of high socio-economic status.


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Record No. 8575
Record ID 008575
Publication type Journal Article
Title The Correlation Between Ultrasound-Measured Fetal Heart Rate and Gestational Age in a Normal Pregnant Nigerian Population
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Eze, U. C.; Okaro, A. O.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6(1)
Pages 73-77
Language English
Descriptor Heart Rate, Fetal; Gestational age; Pregnant Women
Descriptor-Geographic Nigeria
Abstract A total of 400 apparently healthy pregnant women with singleton fetuses from Enugu, Southeast Nigeria were randomly selected for the study. The aims of the study are to establish : a normogram for fetal heart rate (FHR) and the relationship between fetal heart rate and gestational age (GA) by 2-D ultrasound. Crown rump length measurement was used for estimating GA in the first trimester while femur length and biparietal diameter measurements were used for estimating GA in the second and third trimesters. Result shows that the normal range of FHR was 120 to 162 beats per minute (BPM). There was a statistically significant negative correlation of FHR with GA in the first, second, third and combined trimesters as the coefficient of correlation, r = -0.652, -0.736, -0.8185 and -0883 respectively. The study shows that a unit increase in GA decreases the FHR by 32, 15, 12.6 and 13 in the first, second, third and combined trimesters respectively. Results suggest that FHR measurement should be done routinely as one of the essential parameters for the assessment of fetal well being by ultrasound.


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Record No. 8574
Record ID 008574
Publication type Journal Article
Title Safety Awareness in Selected X-ray Diagnostic Centres in Surulere and Ikeja Local Government Areas of Lagos State, Nigeria.
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Aweda, M. A.; Awosanya, G. O.
Journal Title Nigerian Journal of Health and Biomedical Sciences
Date of publication 2007
Volume and n° 6(1)
Pages 62-72
Language English
Descriptor Equipment Safety; Radiology; X-Rays
Descriptor-Geographic Nigeria
Abstract Background: Health hazards are associated with exposure to ionizing radiations such as x-rays. Many private x-ray diagnostic clinics in Lagos State operate with inadequate safety and protection devices, which make the conditions unsafe to patient and environment. Objective: To assess the working conditions, protection measures put in place, safety awareness and attitudes of both employees and employers to safety and protection in radiodiagnostic centers in Surulere and Ikeja Local Government Areas.Methodology: Questionnaires were used for collecting information on socio-demographic data, occupational history, activities, working conditions, knowledge and experience of radiation hazards in x-ray centers. Interviews were conducted with Heads of Departments and Radiologists using the checklist adapted from the International Atomic Energy AgencyResults: 88.9 of the participating centers had adequate space and some safety assessment performed prior to installation of the facility. 81.5 had few basic protection devices. Only 40.7employed adequate and qualified staff while 25.9 provided personnel training and 22.2 had quality control programme. 14.8 had radiation protection programme. 60.2of respondents were aware of health hazards associated with radiation exposures, 57.8 of which were males. Conclusion : Operation conditions in most private diagnostic centers are below standard due to grossly inadequate provision of safety and protection devices. Employment of qualified staff and continuous education need be emphasized and enforced


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Record No. 8573
Record ID 008573
Publication type Journal Article
Title Mortality rate in Sickle Cell Disease Patients in Crisis at a Haematology Day Care Unit (HDCU) in Nigeria
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Olabode, J. O.; Shokunbi, W. A .
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6(1)
Pages 63-66
Language English
Descriptor Hemoglobin SC Disease; Mortality; Patients
Descriptor-Geographic Nigeria
Abstract The Haematology Day Care Unit (HDCU) of the University College Hospital, Ibadan, Nigeria was established in 1975 with the main goal of providing immediate and specialized care to haematological emergencies, particularly sickle cell disease (SCD) patients. Since inception, a systematic analysis of its effectiveness has not been done, hence this study. A retrospective study of all registered patients attending the Haematology Day Care Unit of the University College Hospital, Ibadan, over a one-year period was conducted and analyzed. Demographic data, diagnosis, treatment received, outcome of such treatment as well as laboratory parameters were extracted from HDCU register and the data were then analysed using descriptive statistics. A total of 890 patients were seen during the period, January and December 2001, out of which 520 were sickle cell disease patients (HbSS accounted for 508 (92.7) cases and HbSC, 40 (7.3) cases). The mean age of the SCD patients was 25.8years, the median, 23years and the mode, 18years. The mean PCV was 21.2, median, 21.0 and mode, 20. Majority (246 or 47.3) of the patients were between 20 and 30 years, the lowest frequency being in the 50years group (14 or 2.7). One patient died during the period under review (31year old female with HbSC disease), giving a mortality rate of 2 per 1000 patients


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Record No. 8572
Record ID 008572
Publication type Journal Article
Title A Review of Chest Pain in Nigerian Hypertensive Patients Presenting to the Out-Patient's Clinic of a Teaching Hospital
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Oke, D. A.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6(1)
Pages 58-62
Language English
Descriptor Chest Pain-epidemiology; Hypertension-epidemiology; Ambulatory Care Facilitie
Descriptor-Geographic Nigeria
Abstract In a prospective 6-month study, chest pain was reviewed in hypertensive man above 40 years and post menopausal women on antihypertensive therapy. The subjects were made up of 230 volunteers made up of 101 males and 129 females. Their mean age was 54.5 + 10 years (males 51.3 + 8.9 years vs. female 53.3 + 9.8 years). Forty seven percent of subjects admitted to pain as being located in the retrosternal area, in 38 it was cited at the precordial area and the remainder (9) cited the pain on the right side of the chest and 6 submamary. Twenty six percent and 22 of subjects described pain as being pressure like or dull consecutively. In 42 of patients pain was aggravated by exertion, in 32 of subjects pain had no aggravating factor, 14 and 3 had pain aggravated by hunger and the use of non steroidal anti-inflammatory agents. In the remaining 9 pain was aggravated by breathing particularly during the inspiratory phase of respiration. The relieving factors described include rest in 34, analgesia in (25), change of position in 4 and antacid in 12. In the remaining 25 no relieving factor was identified. Pain radiation was described was mainly to the epigastrium. Based on the symptoms, 11 had all the three parameters of pain description suggestive of angina pectoirs. 5 of patients had symptom suggestive of atypical angina and 17 had just one character present and considered non cardiac. The difference in serum cholesterol level in patients described as having classic angina and atypical were statistically significantly higher than those in subjects who did not complain of chest pain. Patients with atypical chest pain had the highest blood pressure; those with non cardiac pain had the highest WHR while those with no pain had the highest BMI. A proper approach to patients with chest pain irrespective of how trivial it may seem, should include a careful description and characterization of the chest pain, careful and a thorough physical examination. A rational and judicious utilisation of facilities should be employed carrying out the available investigations and possibly following chest pain protocols. .


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Record No. 8571
Record ID 008571
Publication type Journal Article
Title Laboratory Survey of Significant Bacteriuria in a Family Practice Clinic - Is the Spectrum of Causative Agents Changing?
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Oduyebo, O. O.; Ayankogbe, O. O.; Adedokun, A. A.; Ogunsola, F. T.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6(1)
Pages 52-57
Language English
Descriptor Urinary Tract Infections-therapy; Bacteriuria Drug Resistance Spectrum Analysis Laboratories
Abstract Urinary tract infection correlates with significant bacteriuria. Empiric and definitive therapy depends on the sensitivity pattern of the causative agents, so it is essential to keep abreast of changes in the causative organisms. This study was carried out to determine the causative agents of significant bacteriuria and their antibiotic sensitivity pattern. Mid stream urine specimens were collected from all patients attending the Family Medicine Clinic of the Lagos State University Teaching Hospital, Ikeja Lagos in July and August of 2005. The urine specimens were transported on ice to the Medical Microbiology and Parasitology Department of the College of Medicine, Idi-Araba. Significant bacteriuria was determined by the standard loop method. Culture was performed on MacConkey agar (oxoid) and blood agar base (Oxoid) and Isolates were identified by standard laboratory methods. Antibiotic sensitivity was by disc diffusion method. Four hundred and fifty urine specimens surveyed for bacteria were from 251 females (55.8) and 199 males (44.2) with age range 13 to 89 years. Ninety four patients (20.9) had significant bacteriuria and 14 were symptomatic, making the prevalence rate of symptomatic bacteriuria 3.1. Out of 91 patients who had been on antibiotics, a significantly higher proportion (52) had bacteriuria while only 13.4 of those who had not been on antibiotics had bacteriuria. Klebsiella and Enterobacter species were more commonly isolated than E. coli. Most of the isolates were resistant to cotrimoxazole (89), tetracycline (69.1) and amoxicillin (88.1) and amoxicillin (88.1). Sensitivity rates to the urinary antiseptics ranged from 54.2 to 55.9. Many of the bacteria were sensitive to ofloxacin (92.9)), ciprofloxacin (84.7), cefotaxime(72.9), ceftriaxone(86.4) and ceftazidime( 88.1). Sensitivity to the aminoglycosides ranged from 57.7 to 59.3


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Record No. 8570
Record ID 008570
Publication type Journal Article
Title Analysis of Fallopian Tubes seen in the Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria:- An Histopathological Survey
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Izegbu, M. C.; Amole, O. O.; Shittu, L. A.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6 (1)
Pages 49-51
Language English
Descriptor Fallopian Tubes-physiopathology; Salpingitis Pregnancy, Tubal
Abstract OBJECTIVE: The aim of this study is to appraise the major diseases of the fallopian tubes and causes of damage in this environment. MATERIALS AND METHODS: A retrospective study of a 4-year review of consecutive fallopian tube specimens received at the Department of Morbid Anatomy of the Lagos State University Teaching Hospital (LASUTH), Ikeja, Lagos, conducted between 1st of May, 2001 and 31st July, 2005. RESULTS: Over the study period, a total of 237 fallopian tubes were studied. The ages of the patients range from 18 to 54 years with the peak incidence in the 21 to 30 years with the median age of 26. 85(46.4) of the specimens received from 183 patients had ages indicated. Ectopic pregnancy is the commonest indication for sending fallopian tubes to the laboratory for investigation in 63.9 of cases. No case of cancer of the fallopian tubes or tuberculous salpingitis was seen in this study. CONCLUSION: Tubal pregnancy is the commonest indication for sending fallopian tubes to the laboratories for analysis in 63.9 of cases. Malignant tumours of the fallopian tubes and tuberculous salpingitis are rare in this environment.


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Record No. 8569
Record ID 008569
Publication type Journal Article
Title The Effects of Lateral Wedge Insole in the Management of Patients with Varus Osteoarthritis of the Knee
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Akinbo, S. R.; Iko, A. O.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6(1)
Pages 35-37
Language English
Descriptor Osteoarthritis-diagnosis; Patellofemoral Pain Syndrome Disability Evaluation Therapeutics
Descriptor-Geographic Nigeria
Abstract Although insufficient evidence supports the application of lateral wedge insole (LWI) as a non-operative treatment for medial/varus osteoarthritis of the knee joint, objective evaluation of its effects on pain, stiffness and functional disability is limited. The purpose of the study therefore was to determine the effect of LWI on the functional disability and symptoms resulting from the medial/varus osteoarthritis of the knee.Fifty (50) out of 76 patients referred for physiotherapy with diagnosis of varus osteoarthritis of the knee joint participated in this study. The 50 subjects were randomly assigned into 2 groups of 25 patients each. Group A (Experimental), were treated with thermal therapy, massage and LWI. Group B (Control), were treated with thermal therapy and massage only. The outcome measures included knee pain, knee stiffness and functional disability. These parameters were statistically analysed pre and post treatment.Results established a significant difference (p0.05) post treatment between the 2 groups for the outcome measures except knee stiffness. It can be inferred from the results that the therapeutic reduction in pain intensity and enhanced physical activities in group A compared with group B was induced by the LWI.These results provide some insight into the functional effects of the LWI on pain, knee stiffness and functional disability of patients with medial osteoarthritis of the knee. This makes the LWI a useful treatment modality in the management of varus osteoarthritis/varum gonarthrosis.


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Record No. 8568
Record ID 008568
Publication type Journal Article
Title Pathological Changes Induced by Chrysobalanus Icaco Seeds
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Edema, M. O.; Omogbai, E. K.; Afijabi, S. A.; Idaewor, P. E.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Language English
Descriptor Chrysobalanaceae; Cholesterol; Alkaline Phosphatase; Aspartate Aminotransferase, Cytoplasmic; Alanine Transaminase
Descriptor-Geographic Nigeria
Abstract The study was to determine possible pathological changes induced by the consumption of C. icaco and possible health implication. Animal feed tests were carried out using varying amounts of the seed mixed with usual mice meals. The result revealed weight loss, and increase in total bilirubin, protein, albumin, globin, cholesterol level, alkaline phosphate and mean serum glutamic - oxaloacetate transaminase and serum glutamic - pyruvic transaminase activities. Possible health implications are discussed.


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Record No. 8567
Record ID 008567
Publication type Journal Article
Title Plasma Ascorbic Acid and Non-Enzymatic Antioxidants Level in Unoperated Cataract Patients
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Olisekodiaka, M. J.; Adedoyin, A.; Onuegbu, A. J.; Ebesunun, M. O.; Agbedana, E. O.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1995-7262
Date of publication 2007
Language English
Descriptor Ascorbic Acid; Antioxidants; Cataract; Free Radicals; Oxidative Stress
Abstract Free radicals have been implicated in the pathology of several diseases including cataract. Ascorbic acid functions as the major chain breaking antioxidant vitamin in the aqueous phase. Bilirubin, albumin and uric acid are regarded as natural antioxidants. There are conflicting reports on plasma concentrations of these antioxidants in cataract patients. 89 subjects consisting of 55 cataract patients and 34 control subjects were recruited for the study. The mean age of the subjects was 61± 11yrs. Mean plasma ascorbic acid level was significantly lower in cataract patients (0.33± 0.27) when compared with age matched control group (0.59 ±0.37) (p 0.05). A significant increase in mean plasma bilirubin was observed in cataract patients when compared to the corresponding controls. Plasma uric acid levels showed a positive correlation with ascorbic acid (r


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Record No. 8566
Record ID 008566
Publication type Journal Article
Title Comparative Studies of Antimicrobial Properties of Cardiospermum Gradiflorum and Cardiospermum Halicacabum
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Banso, A.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6(1)
Pages 31-24
Language English
Descriptor Anti-Infective Agents; Sapindaceae; Plant Extracts; Candida albicans; Escherichia coli; Staphylococcus aureus; Bacillus subtilis; Viridans Streptococci
Descriptor-Geographic Nigeria
Abstract Extracts of Cardiospermum gradiflorum and Cardiospermum halicacabumwere screened for antimicrobial activities against Candida albicans, Escherichia coli, Staphylococcus aureus, Bacillus subtilis and Streptococcus viridans using the agar diffusion method. The two plants produced antimicrobial activities against all the test organisms. C. grandiflorum exhibited higher antimicrobial activity than C. Halicacabum. S.aureus was the most resistant to the extract of C. Gradiflorum among the organisms assayed while E. coli was the most resistant to the leaf extract of C. halicaca. The mimumum inhibitory concentration of the extracts ranged between 35mg/ml and 50mg/ml. Cardiospermum Gradiflorum could be a more effective antimicrobial agent than Cardiospermum halicaca.


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Record No. 8565
Record ID 008565
Publication type Journal Article
Title Azadirachta indica (Neem) Seed Extracts : A Supplement for Culture Medium for Growth of Aspergillus niger
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Adekunle, O. C.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Volume and n° 6(1)
Pages 29-30
Language English
Descriptor Azadirachta; Aspergillus niger; Plant Extracts; Culture Media; Seeds
Abstract The effectiveness of Neem seed extracts (Azadirachta indica A. Juss) was tested against Aspergillus niger isolated from soil to determine whether the neem seed extracts will inhibit or enhance the growth of Aspergillus niger. Three different concentrations of neem seed extracts were prepared 10, 20 and 50. The results showed that the neem seed extracts enhanced the growth of Aspergillus niger from 24 hours of incorporation up to 120 hours. The growth enhancement was also found to increase with concentration of the seed extracts.


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Record No. 8564
Record ID 008564
Publication type Journal Article
Title Effects of Tea Consumption on Plasma Lipids and Lipoproteins in Apparently Healthy Individuals
Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo
Author(s) Onuegbu, A. J.; Fawekun, H. A.; Olisekodiaka, M. J.; Ebesunun, M. O.; Ikaraoha, I. C.; Agbedana, E. O.
Journal Title Nigerian Journal of Health and Biomedical Sciences
ISSN 1595-8272
Date of publication 2007
Language English
Descriptor Tea; Cholesterol, LDL; Cholesterol, HDL; Lipoproteins; Health
Descriptor-Geographic Nigeria
Abstract Possible alterations in total plasma cholesterol, triglyceride, HDL-cholesterol and LDL-cholesterol concentrations were studied in forty healthy human subjects (twenty-two males and eighteen adult females) after twenty eight days of tea consumption. A commercial brand of tea preparation was drunk by each of the subjects and they were made to take two standard cups (4.0g) of tea infusion per day. The result showed a significant decrease in mean HDL-cholesterol and increase in LDL-cholesterol concentrations compared with the mean control values. The mean total cholesterol was statistically unchanged. When the subjects were grouped into males and females, the mean LDL-C concentration was significantly elevated in both male and female groups while the mean HDL-C and triglyceride levels only in female subjects when compared with the corresponding control group. The difference observed in the value of the mean total cholesterol was not statistically significant in individual male and female groups.Findings from this study suggest that tea consumption could affect the metabolism of atherogenic lipid fractions and may thus be important in the aetiology of coronary heart disease



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