Database : AIM Search on : African Journal of Respiratory [Journal] References found : 35 [refine] Displaying: 1 .. 20   in format [Detailed]

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Record No. 13599 Record ID 013599 Publication type Journal Article Title Physiological Mechanisms Underlying the Use of Garcinia Kola Heckel in the Treatment of Asthma Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Ebomoyi, M. I.; Okojie, A. K. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2012 Volume and n° 8(1) Pages 5-8 Language English Descriptor Asthma-therapy; Garcinia kola Xanthones Descriptor-Geographic Nigeria

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Record No. 13598 Record ID 013598 Publication type Journal Article Title Assessment of Lung Function Parameters in Nigerian Males with Diabetes Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Kolawole, B. A.; Erhabor, G. E.; Ikem, R. T. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2012 Volume and n° 7(2) Pages 20-22, tab. Language English Descriptor Respiratory Function Tests; Diabetes Mellitus; Respiratory Function Tests; Male Abstract Despite scarce information on the implications of diabetes for pulmonary function, existing evidence suggests that the respiratory system might also be affected by diabetes. We therefore conducted a cross sectional study of pulmonary function in male Nigerian diabetes patients using spirometric indices. Seventy-six male diabetes patients aged 27-80 years were studied at the Endocrinology and Diabetes Clinic at the Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria. Overall, all lung function parameters/volumes studied were significantly lower in the diabetes patients compared with predicted values p=0.000. Patients' ages correlated negatively with all spirometric indices but there was no significant relationship between lung function and fasting blood sugar, body mass index, or diabetic microvascular complications. The implications of abnormal lung function parameters for respiratory disease in diabetes are unclear. Routine tests of pulmonary function are not presently indicated in Nigerian diabetes patients.

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Record No. 13597 Record ID 013597 Publication type Journal Article Title Five-year Audit of Spirometry at the LASUTH, Ikeja, South-West Nigeria Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Adeyeye, O. O.; Bamisile, R. T.; Brodie-Mends, A. T.; Adekoya, A. O.; Bolarinwa, F. F.; Onadeko, B. O.; Aromokeye, D. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2012 Volume and n° 8(1) Pages 15-17 Language English Descriptor Spirometry; Pulmonary Medicine; Medical Audit; Hospitals, Teaching Descriptor-Geographic Nigeria Abstract Spirometry is a non-invasive tool of importance in respiratory medicine. There is an enormous burden of pulmonary disease worldwide, including in Nigeria. This retrospective study was done to determine the utilisation of spirometry services in the Lagos State University Teaching Hospital (LASUTH). It determined the sources of referral, indications, and pattern of pulmonary abnormalities. This is a retrospective study. An audit was done on the data collected at the Pulmonary Function Laboratory of the LASUTH between September 2006 and October 2011. Spirometry was done using the Gold Standard Vitalograph spirometer. The demographic characteristics of the patients who had spirometry as well as FEV1, (forced expiratory volume in 1 second) FVC (forced vital capacity), and their predicted values were noted. A total of 849 patients had spirometry done over the 5-year period. Slightly more than half were male patients. The mean age of the patient was 50±19 years. There was a steady increase in the number of spirometry tests performed from 2006 reaching a peak in 2009. Thereafter, a sharp decline was seen in 2010 with a steady rise in the first 10 months of 2011. The most common indication for spirometry was in the evaluation and assessment of asthma in 487 patients (57). Most of the referrals for spirometry were from the medical department of the hospital representing 532 (63) patients; 202 (24) of the request were from the general out-patient department by family physicians, while 115 (13) came from the surgical department. The outcome of the ventilatory abnormalities showed that 372 (44) had normal ventilatory indices, 206 (24) had obstructive patterns, 169 (20) had mixed type, while restrictive patterns were seen in 102 (12). We concluded that although spirometry is frequently used in our clinical practice, this can be improved upon.

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Record No. 13596 Record ID 013596 Publication type Journal Article Title Non-Infectious Lung Manifestations of Autoimmune Diseases in Cameroon Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Nana, A. M.; Ngnie, C.; Wandji, A.; Halle, P.; Solange, M. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2012 Volume and n° 8(1) Pages 12-14 Language English Descriptor Autoimmune Diseases-diagnosis; Lupus Erythematosus, Systemic HIV Infections Lung Signs and Symptoms Descriptor-Geographic Cameroon Abstract Autoimmune (AI) diseases are secondary to lack of tolerance against self antigens. They may have systemic or organ-specific manifestations. All lung structures can be affected. The aim of our study was to determinate clues of diagnosis and treatment facilities for noninfectious lung manifestations of AI disease. A multi-centre retrospective study was performed from January 2006 to July 2009 in Douala, Cameroon. Twenty-nine patients were included (59female), with an average age of 42±10 (18-58) years. The lung was the discovery mode of AI disease in 79. Systemic lupus erythematosus (SLE) was the most frequently observed AI disease (48). Thirty-eight percent have at least one cure against pleural or smear-negative tuberculosis. Clinical anomalies found were: cough 79, dyspnoea 69, and crackles 41. Morphological anomalies were interstitial lesions in 55of chest Xrays, 50of ground grass pattern, and 25of fibrosis on CT scan; chest function test showed restrictive pattern in 41. Three (10) patients were HIV positive with a CD4 cell count more than 500/mm³. Two patients underwent talc pleurodesis for recurrent pleural effusion. General steroids were prescribed to all patients, hydroxychloroquine to 31and azathioprine to 21. At the time of writing, 18 patients were still being followed up and 3 (10) had died. AIs exist in many countries. Clues of diagnosis of non-infectious pulmonary involvement are a patient presenting with chronic respiratory symptoms, crackles at physical examination, negative sputum smear, and unusual chest X-ray abnormality for tuberculosis.

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Record No. 13595 Record ID 013595 Publication type Journal Article Title Health-Related Quality of Life among Patients with Bronchial Asthma in Ile-Ife, Nigeria Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Adeniyi, B. O.; Erhabor, G. E; Awopeju, F. O.; Obaseki, D. O.; Adewole, O. O.; Burney, P . Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2012 Volume and n° 8(1) Pages 9-11, tab. Language English Descriptor Asthma; Quality of Life; Patients Descriptor-Geographic Nigeria-Ile-Ife;

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Record No. 13461 Record ID 013461 Publication type Journal Article Title Exercise-Induced Asthma in Adult Nigerian Asthma Patients: a Comparison of Step Test, free Running, and Bicycle Ergometer Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Machira, E. P. M.; Obimbo, E. M.; Wamalwa, D.; Gachare, L. N. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2011 Volume and n° 7(1) Pages 8-10, fig., tab. Language English Descriptor Asthma-diagnosis; Exercise Test Adult Descriptor-Geographic Nigeria Abstract Exercise is not only a very common precipitant of acute asthmatic episodes but also a potent non-pharmacological test for diagnosis of asthma. Different exercise protocols have been used; however a simple exercise test would be valuable and helpful for detecting exerciseinduced asthma (EIA). The main goal of this study was to compare the exercise-inducing capacity of free running, step test, and cycle ergometer. Forty-eight asthma patients performed and completed the exercise tests reaching at least 80-85of the predicted maximal heat rate. The peak expiratory flow (PEF) values and heart rate (HR) were used to monitor pulmonary function post-exercise and the intensity of the exercise respectively. The PEF values were measured at baseline, immediately after the exercise then at 5-minute intervals up to 30 minutes. Subjects who reached the percentage fall in PEF 15were considered positive for EIA. Free running was found to be the most asthmagenic exercise followed by the step test and cycle ergometer: 36 subjects (75) for free running versus 27 subjects (56) for step test, versus 24 subjects (50) for cycle ergometer. There is a strong and significant correlation between the percentage fall in PEF of cycle ergometer and step test (r=0.61, p0.001). Free running produced the most positive result. However, the step test is a safe, simple, portable, and readily available instrument which compares well with laboratory-based cycle ergometer. We conclude that the step-test is an inexpensive and responsive exercise protocol for assessing and evaluating asthmatics in low-income countries.

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Record No. 13460 Record ID 013460 Publication type Journal Article Title Assessment of Inhalation Technique among Asthmatic Children and their Carers at the Kenyatta National Hospital, Kenya Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Machira, E. P. M.; Obimbo, E. M.; Wamalwa, D.; Gachare, L. N. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2011 Volume and n° 7(1) Pages 19-22 Language English Descriptor Asthma; Inhalation; Adrenal Cortex Hormones; Child Descriptor-Geographic Kenya Abstract The aim of this study was to evaluate the correctness of use of pressurised metered-dose inhalers and spacer devices and to determine the common errors in the inhalation technique and factors associated with incorrect technique. The descriptive cross-sectional survey took place in the Kenyatta National Hospital, Nairobi, Kenya. Eighty-two asthmatic children aged 6 months to 12 years (median age 45 months, 56males) on inhaler medications and their carers were recruited into the study and assessed for correctness of inhalation technique. Of the 82 subjects, only 37 (45.1) performed all the essential steps of the inhalation technique correctly. The commonest errors were failure to take adequate breaths after actuation of inhaler (45) and not shaking the inhaler before use (18). The characteristics of correct and incorrect users are mainly similar. It was concluded that the majority (55) of asthmatic children and their carers do not perform the inhalation technique correctly. Electronic Access :  Full Text-1

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Record No. 13459 Record ID 013459 Publication type Journal Article Title Knowledge and Views of Paediatricians about Pulse Oximetry: a Nationwide Online Survey in Nigeria Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Orimadegun, A. E.; Ogunbosi, B. O.; Akinbami, F. O. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2011 Volume and n° 7(1) Pages 14-18 Language English Descriptor Oximetry; Knowledge; Pediatrics Descriptor-Geographic Nigeria Abstract Pulse oximetry is a non-invasive method of measuring oxygen saturation in clinical settings. This study was carried out to determine the level of knowledge and competencies relating to pulse oximetry and the ability to interpret the information. We conducted a nationwide, multi-centre, and questionnaire-based online survey between January and June 2010. A 32-item questionnaire relating to the use of pulse oximetry in children was answered by 224 in-training and 157 qualified paediatricians (median duration of practice 6 years) working in 24 states in Nigeria. Knowledge of pulse oximetry was evaluated on a scale of 0-100. Data were analysed using Chi-square and t-test statistics at 5level of significance. The overall mean test score was 36.6±20.8(range 0-76.5). The mean knowledge score among in-training and qualified paediatricians was 35.4±19.1and 38.3±23.1, respectively (p0.05). Only 16.3of the respondents answered all three questions correctly relating to the relationship between oxygen saturation and partial pressure of oxygen. Pertaining to the accuracy of pulse oximeters, 3.9of the respondents answered all 14 questions correctly. On indications for use of pulse oximetry, 29correctly answered all nine questions. Only 18of respondents correctly answered the seven questions on interpretation of pulse oximeter reading. Some 73of respondents believed that training in the use of pulse oximetry was inadequate. A significant proportion of the paediatricians were untrained in pulse oximetry, lacked knowledge of basic principles, and made serious errors in interpretation of readings from pulse oximeters. We suggest that medical schools and residency training programmes place more emphasis on teaching the principles and uses of pulse oximetry. Electronic Access :  Full Text-1 Full Text-2 Full Text-3 Full Text-4

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Record No. 13458 Record ID 013458 Publication type Journal Article Title Assessment of Clinical Features and Haematocrit Levels in Detection of Hypoxaemia in Sick Children Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Emodi, I. J.; Ikefuna, A. N.; Ubesie, A. C.; Chukwu, B. F.; Chinawa, J. M. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2012 Volume and n° 7(1) Pages 11-13 Language English Descriptor Anoxia; Hematocrit; Prevalence; Child; Hospitals, Teaching Descriptor-Geographic Nigeria Abstract This cross-sectional study was to determine the prevalence of hypoxaemia among sick children in Enugu State University Teaching Hospital, Enugu, Nigeria and correlate it with clinical features and haematocrit levels. Ninety-two (92) sick children aged 2-48 months hospitalised at the teaching hospital were recruited after obtaining consent from their carers. The prevalence of hypoxaemia in this study, defined by oxygen saturation of less than 90, was 13, and was not dependent on age or sex. A higher proportion of subjects with hypoxaemia had tachypnoea (81.8), compared with those without (18.2) (?² = 1.69; p=0.19). The sensitivity of using tachypnoea alone to predict hypoxaemia was 18.4while the specificity was 92.3. The presence of hypoxaemia predicted poor outcome; 66.7of those that died had hypoxaemia. The difference was statistically significant (?2= 17.9; p=0.00). Tachypnoea had a poor sensitivity although good specificity in predicting hypoxaemia. Presence of hypoxaemia connotes poor prognosis. We recommend that finger pulse oximeters, which are cost effective, should be routinely available at hospitals in developing countries, so that hypoxaemia can be detected earlier and more intensive management instituted Electronic Access :  Full Text-1 Full Text-2 Full Text-3 Full Text-4

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Record No. 13457 Record ID 013457 Publication type Journal Article Title Systematic Chest Radiography during Pre-Employment Check-Up Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Kouamé, N.; Ngoan-Domoua, A. M.; Konan, A. N. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2012 Volume and n° 7(23) Pages 15-17 Language English Descriptor Radiography; Employment; Personnel Selection; Cardiovascular Diseases; Mediastinal Diseases; Tropical Climate Abstract The aim of this study was to specify the importance of chest radiography during pre-employment check-ups in the tropical environment. A cross-sectional study of chest X-rays of 2540 apparently healthy job applicants in seven private companies in Abidjan, Côte d'Ivoire, was carried out over a 5-year period. The chest X-rays were performed in posterior-anterior, frontal, standing position. Two senior radiologists performed a double-blind study in search of parietal, mediastinal, and pleuroparenchy-matous abnormalities. The 2540 subjects were all males with ages ranging between 20 and 36 years. In 93of the cases (2372 job applicants) the frontal chest X-ray was normal but 168 (7) presented abnormal images. The observed lesions were dominated by cardiomegaly (102 cases) followed by pulmonary parenchymatous lesions (35 cases), and by pleural liquid effusions (10 cases). The parenchymatous abnormalities were represented by 35 evolutional lesions in the form of 12 apical parenchymatous infiltrates, 7 excavated apical pneumopathies, and 16 non-excavated condensations. The 10 cases of pleural abnormality were encysted pleuritis. Frontal chest radiology can be useful in pre-employment check-ups in the tropical environment by helping to screen for contagious pulmonary lesions that may be undetected at a clinical examination Electronic Access :  Full Text-1 Full Text-2 Full Text-3

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Record No. 13456 Record ID 013456 Publication type Journal Article Title A Synopsis of Asthma Research in Nigeria between 1970 and 2010 Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Ozoh, O. B.; Bandele, E. O. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2012 Volume and n° 7(23) Pages 5-11, fig., tab. Language English Descriptor Asthma-epidemiology; Asthma-diagnosis; Asthma-therapy; Psychophysiologic Disorders Risk Factors Review Electronic Access :  Full Text-1 Full Text-2 Full Text-3

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Record No. 13455 Record ID 013455 Publication type Journal Article Title Assessment of Lung Function Parameters in Nigerian Males with Diabetes Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Kolawole, B. A.; Erhabor, G. E.; Ikem, R. T. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2012 Volume and n° 7(23) Pages 20-22, fig., tab. Language English Descriptor Diabetes Mellitus; Lung Diseases; Spirometry; Male; Respiratory System Descriptor-Geographic Nigeria Abstract Despite scarce information on the implications of diabetes for pulmonary function, existing evidence suggests that the respiratory system might also be affected by diabetes. We therefore conducted a crosssectional study of pulmonary function in male Nigerian diabetes patients using spirometric indices. Seventy-six male diabetes patients aged 27-80 years were studied at the Endocrinology and Diabetes Clinic at the Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria. Overall, all lung function parameters/volumes studied were significantly lower in the diabetes patients compared with predicted values p=0.000. Patients' ages correlated negatively with all spirometric indices but there was no significant relationship between lung function and fasting blood sugar, body mass index, or diabetic microvascular complications. The implications of abnormal lung function parameters for respiratory disease in diabetes are unclear. Routine tests of pulmonary function are not presently indicated in Nigerian diabetes patients. Electronic Access :  Full Text-1 Full Text-2 Full Text-3

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Record No. 13454 Record ID 013454 Publication type Journal Article Title Obstructive Sleep Apnoea Hypopnoea Syndrome (OSAHS) Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Mbata, G. C.; Chukwuka, J. C. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2012 Volume and n° 7(23) Pages 12-15 Language English Descriptor Sleep Apnea, Obstructive-diagnosis; Sleep Apnea, Obstructive-physiopathology; Sleep Apnea, Obstructive-therapy; Descriptor-Geographic Nigeria Electronic Access :  Full Text-1 Full Text-2 Full Text-3

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Record No. 11259 Record ID 011259 Publication type Journal Article Title Home Management of Acute Respiratory Infections in a Nigerian District Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Ukwaja, K. N.; Olufemi, O. A. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2010 Language English Descriptor Respiratory Tract Infections; Pneumonia; Malaria; Child Descriptor-Geographic Nigeria Abstract Globally, over 2 million children die annually from acute respiratory infections (ARIs) especially pneumonia. ARI symptoms (cough and difficult/fast breathing) frequently overlap with those of malaria. In Nigeria, children with these pneumonia symptoms are frequently overlooked by the home management strategy that seeks to treat all childhood fevers as malaria. The aim of the study was to determine the prevalence of overlap of fever and ARI symptoms, the timeliness of care-seeking and the type of care sought for ARI with or without fever at community level. From a district, 420 households with 420 children aged over 5 years who had been sick with cough within 2 weeks of the survey were selected through systematic random sampling and their carer interviewed about the child's illness. Of the 413 children who had been sick with cough, 21reported overlapping symptoms of fever, cough and difficult/fast breathing (DFB). Of these, 27received antimalarials alone. Sixty percent of children with ARI received antibiotics and 59received care within 24 hours of symptom recognition. Carers of infants and children with DFB were more likely to seek care within 24 hours of symptom recognition (both p 0.001). Most (45) of the antibiotics used were obtained from patent medicine dealers. It was concluded that a large percentage of children have malaria and pneumonia symptom overlap; and a significant proportion of these cases are mismanaged as malaria in the community. The role of patent medicine dealers in recognising and appropriately treating ARI should be explored.

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Record No. 11258 Record ID 011258 Publication type Journal Article Title Practice of Asthma Management among Doctors in South-East Nigeria Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Ayuk, A.; Iloh, K.; Obumneme-Anyi, I.; Ilechukwu, G.; Oguonu, T. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2010 Volume and n° 6(1) Pages 14-17, fig., tab. Language English Descriptor Asthma; Disease Management; Community Health Aides; Child Descriptor-Geographic Nigeria Abstract The major role of airway inflammation in childhood asthma has been recognised for more than a decade, and anti-inflammatory drugs now form the mainstay of treatment. In order to optimise treatment and achieve a better outcome, different guidelines have been introduced for asthma management. Examining the practice of the medical practitioners who manage asthma will help establish the gaps and provide informed advice on the current national and international guidelines. Our objective was to investigate the appropriate treatment of acute bronchial asthma by medical practitioners in south-east Nigeria. Two hundred and eighty-five doctors were interviewed using a structured questionnaire. Evaluation for differences in asthma management by doctors with different years of practice and heath facilities was carried out. Results were analysed with Epi info version 3.5. We concluded that management based on newer trends in childhood asthma management and adherence to management guidelines is less common among doctors that work in non-tertiary health facilities and among doctors that graduated more than 15 years ago or less than 5 years ago. This needs to be improved for optimal management of these patients. The need for regular continuing medical education for all doctors cannot be over emphasised.

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Record No. 11257 Record ID 011257 Publication type Journal Article Title Tuberculosis Registers in Africa: a Review Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Nturibi, R. M. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2010 Volume and n° 6(1) Pages 5-10, fig, tab Language English Descriptor Tuberculosis-prevention & control; Tuberculosis-epidemiology; Directory Review Descriptor-Geographic Africa

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Record No. 11256 Record ID 011256 Publication type Journal Article Title Occupational Asthma: a Review of Current Concept Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Adewole, F. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2010 Volume and n° 6(1) Pages 6-10, fig., tab. Language English Descriptor Asthma; Risk factors; Occupational Diseases; Review Descriptor-Geographic Nigeria

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Record No. 10915 Record ID 010915 Publication type Journal Article Title Ventiliatory Function in Nigerians with Type 2 Diabetes Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Ozoh, O. B.; Okubabejo, N. U.; Bandele, E. O.; Chukwu, C. C . Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2010 Volume and n° 5(2) Pages 18-22, tab. Language English Descriptor Diabetes Mellitus, Type 2; Pulmonary Ventilation; Signs and Symptoms Descriptor-Geographic Nigeria Abstract Reduced ventilatory function in type 2 diabetes has been reported in other parts of the world. This study aimed to assess the ventilatory function in Nigerians with type 2 diabetes and its relationship to the duration of symptoms of diabetes, glycaemic control, age, and body mass index (BMI). One hundred and one (101) patients with type 2 diabetes were matched to 104 control subjects with normal glucose tolerance. Historical and clinical data were documented and venous blood sampled for HbA1c in the diabetes group. Peak expiratory flow rate (PEFR), forced expiratory volume in 1 second (FEV1), forced vital capacity (FVC) and the ratio of the FEV1 to the FVC as a percentage (FEV1/ FVC) were measured for both groups. Study subjects and controls were similarly matched. Mean PEFR (L/s), FEV1 (L), and FVC (L) were 5.6±2.24, 2.36±0.74, and 2.94±0.90, respectively, in the diabetes group and 6.31±1.62, 2.58±0.62, and 3.19±0.79, respectively, in the control group (p=0.006, 0.02, and 0.03, respectively). The FEV1/FVCwas 81.90±24.17 in the diabetes group and 81.26±5.99 in controls (p= 0.86). Compared with predicted values for Nigerians, 11 (11) of diabetes subjects had restrictive lung disease and 6 (6) had obstructive lung disease while 1 (1) of controls had restrictive lung disease and 5 (5) had obstructive lung disease (c2=9.46, p=0.009). In multivariate analysis, age was inversely related to the PEFR (p=0.04). BMI was inversely related to PEFR, FEV1, and FVC (p= 0.01, 0.001, 0.002, respectively). Duration of diabetes was also inversely related to FEV1 (p= 0.02). HbA1c was not significant for any ventilatory index. It was concluded that Nigerians with type 2 diabetes have significantly lower ventilatory function (with a restrictive pattern), compared with matched controls. Symptom duration, age, and BMI are independent determinants of ventilatory function. Electronic Access :  Full Text-1

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Record No. 10914 Record ID 010914 Publication type Journal Article Title Toluene Diisocyanate-Linked Ocupational Airflow Obstruction and Peak Expiratory Flow Rate Patterns among Foam Makers Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Inem, V.; Onubeze, D. P. M.; Osiji, C. U. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2010 Volume and n° 5(2) Pages 12-16, tab. Language English Descriptor Toluene 2,4-Diisocyanate; Pulmonary Ventilation; Peak Expiratory Flow Rate; Occupational Exposure Descriptor-Geographic Nigeria Abstract This study looked at the prevalence of respiratory symptoms and airflow obstruction, and peak expiratory flow rate (PEFR) variation between production workers and control workers (both inside and outside work, linked to the foam-making industry at Onitsha, south -east Nigeria. A cross-sectional case control study was conducted among 199 randomly selected workers from five major foam companies.Subjects were grouped into exposed (production workers) and control, and a modified structured four-part Guidelines for Health Surveillance for Isocyanates questionnaire was administered. The workers had their PEFR values individually assessed during work on Friday and before resumption of work the following Monday morning for a period of 6 months. A total of 199 subjects were recruited (129 production workers, 70 control workers). There was a higher proportion of respiratory symptoms among the exposed group (53) compared with the controls (34) (p0.02). It was concluded that airflow obstruction and respiratory symptoms are common among workers in foam industries exposed to toluene diisocyanate. Electronic Access :  Full Text-1

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Record No. 10913 Record ID 010913 Publication type Journal Article Title A Clinician's Guide to 2009 H1N1 Influenza Source of Record WHO Regional Office for Africa, Library, Brazzaville, Congo Author(s) Aston, A. Journal Title African Journal of Respiratory Medicine ISSN 1747-5597 Place of Publication Liverpool Publisher Pan-African Thoracic Society Date of publication 2010 Volume and n° 5(2) Pages 8-11 Language English Descriptor Influenza A Virus, H1N1 Subtype; Influenza A virus; Antiviral Agents; Review Descriptor-Geographic Africa Electronic Access :  Full Text-1

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