An audit of chemical pathology laboratory investigation request forms received at a private tertiary hospital in Nigeria / Chinelo P. Onyenekwu 

Public ISBD Title : An audit of chemical pathology laboratory investigation request forms received at a private tertiary hospital in Nigeria Authors: Chinelo P. Onyenekwu, Author ; Adeyemi O. Dada, Author ; Abiola A. Gbadebo, Author ; Adebamike A. Oshunbade, Author Publisher: Maiduguri [Nigeria - Borno State] : Medical and Dental Consultants Association of Nigeria - Nigerian Medical Association Publication Date: 2017 Series: Borno Medical Journal, ISSN 2437-1734 No. 14(1) Pagination: p.85-90 Layout: Journal Article ISSN (or other code): 2437-1734 Languages : English Keywords: Laboratories  Clinical Audit  Decision Making  Tertiary Care Centers  Nigeria Abstract: Context: Laboratory testing constitutes an integral part of patient management and has an extensive influence on medical decision-making. The completion of laboratory investigation request forms is a vital aspect of the highly variable pre-analytical phase of laboratory testing.Aim: We aimed to assess the adequacy of completion of investigation request forms received at our laboratory.Methods: An audit of systematically selected laboratory investigation request forms received over a six-month period at our laboratory was performed to assess the degree of completion of these forms by requesting clinicians. Data was analysed using Microsoft Excel®.Results: Two hundred and fifty four request forms were reviewed. None of the reviewed forms was adequately completed. The clinician's contact number was missing in all the request forms. About two-thirds of the request forms did not have the patient's hospital number (66.1%) and the referring clinician's signature (66.9%) available on them. The clinical diagnosis of the patient was not stated in 18.9% of the request forms. The patient's name, gender and age were the most frequently completed parameters in 100.0%, 98.4% and 97.2% of the request forms respectively.Conclusion: Basic information required for the accurate interpretation of laboratory results are missing in several request forms. This may have deleterious impact on laboratory turn around time, healthcare costs and patient management as most medical decisions are influenced by laboratory results Link for e-copy: http://www.bornomedicaljournal.com/pdfs/AN AUDIT OF CHEMICAL PATHOLOGY LABORATOR [...] An audit of chemical pathology laboratory investigation request forms received at a private tertiary hospital in Nigeria [] / Chinelo P. Onyenekwu, Author ; Adeyemi O. Dada, Author ; Abiola A. Gbadebo, Author ; Adebamike A. Oshunbade, Author . - Maiduguri (1414, Nigeria - Borno State) : Medical and Dental Consultants Association of Nigeria - Nigerian Medical Association, 2017 . - p.85-90 : Journal Article. - (Borno Medical Journal, ISSN 2437-1734; 14(1)) . ISSN : 2437-1734 Languages : English Keywords: Laboratories  Clinical Audit  Decision Making  Tertiary Care Centers  Nigeria Abstract: Context: Laboratory testing constitutes an integral part of patient management and has an extensive influence on medical decision-making. The completion of laboratory investigation request forms is a vital aspect of the highly variable pre-analytical phase of laboratory testing.Aim: We aimed to assess the adequacy of completion of investigation request forms received at our laboratory.Methods: An audit of systematically selected laboratory investigation request forms received over a six-month period at our laboratory was performed to assess the degree of completion of these forms by requesting clinicians. Data was analysed using Microsoft Excel®.Results: Two hundred and fifty four request forms were reviewed. None of the reviewed forms was adequately completed. The clinician's contact number was missing in all the request forms. About two-thirds of the request forms did not have the patient's hospital number (66.1%) and the referring clinician's signature (66.9%) available on them. The clinical diagnosis of the patient was not stated in 18.9% of the request forms. The patient's name, gender and age were the most frequently completed parameters in 100.0%, 98.4% and 97.2% of the request forms respectively.Conclusion: Basic information required for the accurate interpretation of laboratory results are missing in several request forms. This may have deleterious impact on laboratory turn around time, healthcare costs and patient management as most medical decisions are influenced by laboratory results Link for e-copy: http://www.bornomedicaljournal.com/pdfs/AN AUDIT OF CHEMICAL PATHOLOGY LABORATOR [...]

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Imatinib theraphy in chronic myeloid leukaemia : review of mechanisms of resistance and therapheutic options in imatinib failure / A. I. Ladu 

Public ISBD Title : Imatinib theraphy in chronic myeloid leukaemia : review of mechanisms of resistance and therapheutic options in imatinib failure Authors: A. I. Ladu, Author ; M. A. Aisha, Author Publisher: Maiduguri [Nigeria - Borno State] : Medical and Dental Consultants Association of Nigeria - Nigerian Medical Association Publication Date: 2017 Series: Borno Medical Journal, ISSN 2437-1734 No. 14(1) Layout: Journal Article ISSN (or other code): 2437-1734 Languages : English Keywords: Leukemia, Myelogenous, Chronic, BCR-ABL Positive  Imatinib Mesylate  Drug Resistance, Neoplasm  Myeloproliferative Disorders  Nigeria Abstract: Chronic myeloid leukaemia is triphasic, clonal malignancy, arising from the haemopoeitic stem cell. It is characterized by the presence of philadelphia chromosome, which result from reciprocal translocation between chromosome 9 and 22. The resulting oncogen- brc-abl has proliferative activity and survival advantage against normal cell and this account for the clinical and laboratory manifestation of this myeloproliferative disorder. Imatinib, a tyrosine kinase inhibitor (TKIs) is currently the first line of treatment, however, one third of patient develope resistance to it, thus necessitating alternative TKIs. Many factors are associated with the development of resistance to imatinib, such as mutation in the brc-abl gene, increase production of the mutant protein and activation of alternatve pathways amongst other causes. The aim of this reveiw is to explore these factors, and also to avaluate current TKIs that are use as alternative in Imatinib resistant cases. Link for e-copy: http://www.bornomedicaljournal.com/pdfs/imatinib theraphy.pdf Imatinib theraphy in chronic myeloid leukaemia : review of mechanisms of resistance and therapheutic options in imatinib failure [] / A. I. Ladu, Author ; M. A. Aisha, Author . - Maiduguri (1414, Nigeria - Borno State) : Medical and Dental Consultants Association of Nigeria - Nigerian Medical Association, 2017 . -  : Journal Article. - (Borno Medical Journal, ISSN 2437-1734; 14(1)) . ISSN : 2437-1734 Languages : English Keywords: Leukemia, Myelogenous, Chronic, BCR-ABL Positive  Imatinib Mesylate  Drug Resistance, Neoplasm  Myeloproliferative Disorders  Nigeria Abstract: Chronic myeloid leukaemia is triphasic, clonal malignancy, arising from the haemopoeitic stem cell. It is characterized by the presence of philadelphia chromosome, which result from reciprocal translocation between chromosome 9 and 22. The resulting oncogen- brc-abl has proliferative activity and survival advantage against normal cell and this account for the clinical and laboratory manifestation of this myeloproliferative disorder. Imatinib, a tyrosine kinase inhibitor (TKIs) is currently the first line of treatment, however, one third of patient develope resistance to it, thus necessitating alternative TKIs. Many factors are associated with the development of resistance to imatinib, such as mutation in the brc-abl gene, increase production of the mutant protein and activation of alternatve pathways amongst other causes. The aim of this reveiw is to explore these factors, and also to avaluate current TKIs that are use as alternative in Imatinib resistant cases. Link for e-copy: http://www.bornomedicaljournal.com/pdfs/imatinib theraphy.pdf

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Morbidity and mortality associated with conservative management of spinal cord injury in Makurdi, north central Nigeria / Yongu T. Williams 

Public ISBD Title : Morbidity and mortality associated with conservative management of spinal cord injury in Makurdi, north central Nigeria Authors: Yongu T. Williams, Author ; Elachi C. Itodo, Author ; D. Daniel Mue, Author ; N. Joseph Kortor, Author ; Stephen Atokolo, Author Publisher: Maiduguri [Nigeria - Borno State] : Medical and Dental Consultants Association of Nigeria - Nigerian Medical Association Publication Date: 2017 Series: Borno Medical Journal, ISSN 2437-1734 No. 14(1) Pagination: p.73-77, tab. Layout: Journal Article ISSN (or other code): 2437-1734 Languages : English Keywords: Spinal Cord Injuries - complications  Morbidity  Hospitals, Teaching  Nigeria Abstract: Background Spinal cord injury is commonly associated with morbidity and mortality. This is further worsened by inadequate rehabilitation because of dearth of infrastructure, equipment and personnel Objectives:To identify the complications and causes of death in traumatic spinal cord injury patients.Methodology: A 4-year retrospective review of all traumatic spinal cord injured patients treated at Benue State University Teaching Hospital Makurdi was conducted. The information on age, sex, occupation, cause, associated injuries, level of injury, neurological deficit, American spinal cord injury association (ASIA) score at presentation, complications and outcome were obtained from medical records department. Data were analyzed using Statistical Package for Social Sciences (SPSS) 17.0 (SPSS Inc. Chicago, IL, USA).Results: There were 62 patients with a mean age of 36.02±1.67 years (range 8-77 years) consisting of 54 males and 8 females giving a male to female ratio of 6.8:1. They included students 13(21%) and farmers 10(16.1%). Road traffic crash accounted for 35(56.5%). Majority had cervical spine injury 22(62.8%) and accounted for complications in 20(36.4%). Bed sores occurred in 22(35.5%). ASIA A had the highest frequency of complications 22(35.5%). Eleven patients died giving a case fatality of 31.4%. The patients died from respiratory failure 4(36.4%) and sepsis 2(18.2%). Conclusion: Many complications including bed sores and orthostatic pneumonia result from spinal cord injury leading to high morbidity and death from sepsis and respiratory failure Link for e-copy: http://www.bornomedicaljournal.com/pdfs/MORBIDITY AND MORTALITY ASSOCIATED WITH  [...] Morbidity and mortality associated with conservative management of spinal cord injury in Makurdi, north central Nigeria [] / Yongu T. Williams, Author ; Elachi C. Itodo, Author ; D. Daniel Mue, Author ; N. Joseph Kortor, Author ; Stephen Atokolo, Author . - Maiduguri (1414, Nigeria - Borno State) : Medical and Dental Consultants Association of Nigeria - Nigerian Medical Association, 2017 . - p.73-77, tab. : Journal Article. - (Borno Medical Journal, ISSN 2437-1734; 14(1)) . ISSN : 2437-1734 Languages : English Keywords: Spinal Cord Injuries - complications  Morbidity  Hospitals, Teaching  Nigeria Abstract: Background Spinal cord injury is commonly associated with morbidity and mortality. This is further worsened by inadequate rehabilitation because of dearth of infrastructure, equipment and personnel Objectives:To identify the complications and causes of death in traumatic spinal cord injury patients.Methodology: A 4-year retrospective review of all traumatic spinal cord injured patients treated at Benue State University Teaching Hospital Makurdi was conducted. The information on age, sex, occupation, cause, associated injuries, level of injury, neurological deficit, American spinal cord injury association (ASIA) score at presentation, complications and outcome were obtained from medical records department. Data were analyzed using Statistical Package for Social Sciences (SPSS) 17.0 (SPSS Inc. Chicago, IL, USA).Results: There were 62 patients with a mean age of 36.02±1.67 years (range 8-77 years) consisting of 54 males and 8 females giving a male to female ratio of 6.8:1. They included students 13(21%) and farmers 10(16.1%). Road traffic crash accounted for 35(56.5%). Majority had cervical spine injury 22(62.8%) and accounted for complications in 20(36.4%). Bed sores occurred in 22(35.5%). ASIA A had the highest frequency of complications 22(35.5%). Eleven patients died giving a case fatality of 31.4%. The patients died from respiratory failure 4(36.4%) and sepsis 2(18.2%). Conclusion: Many complications including bed sores and orthostatic pneumonia result from spinal cord injury leading to high morbidity and death from sepsis and respiratory failure Link for e-copy: http://www.bornomedicaljournal.com/pdfs/MORBIDITY AND MORTALITY ASSOCIATED WITH  [...]

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Pattern of presentation and management of urolithiasis at federal medical centre, Nguru, Nigeria / B. M. Abubakar 

Public ISBD Title : Pattern of presentation and management of urolithiasis at federal medical centre, Nguru, Nigeria Authors: B. M. Abubakar, Author ; A. Abubakar, Author ; I. E. Suleiman, Author ; B. S. Makama, Author ; A. A. Abdulhafeez, Author ; M. G. Gashua, Author Publisher: Maiduguri [Nigeria - Borno State] : Medical and Dental Consultants Association of Nigeria - Nigerian Medical Association Publication Date: 2017 Series: Borno Medical Journal, ISSN 2437-1734 No. 14(1) Pagination: p.63-70, fig., tab. Layout: Journal Article ISSN (or other code): 2437-1734 Languages : English Keywords: Urolithiasis - diagnosis  Urolithiasis - therapy  Disease Management  Retrospective Studies  Nigeria Abstract: Background: Urolithiasis has been with mankind since ancient time. Although it is more common in the developed world, the pattern of presentation in the developing countries is tending towards that of developed countries. Objectives: To evaluate the pattern of presentations and treatments offered to patients with urolithiasis over the last 2 years at Federal Medical Centre (FMC), Nguru.Materials and Methods: The study is a 2-year retrospective review of patients managed for urolithiasis at FMC Nguru. The patients' bio-data, pattern of presentation and radiological features of the stones, as well as the treatment given to the patients, were reviewed.Results: The records of 55 patients were reviewed; the mean age was 24.1 years with a range of 1.5 to 70years. The male to female ratio was 10:1. The most common presenting symptom was painful micturition in 21 patients (38.18%). The total number of stones extracted was 58, one patient had multiple right renal pelvic calculi, another had bilateral renal pelvic stone and the third patient had bladder and distal ureteric stone. Two patients (3.64%) expelled their calculi while awaiting surgery, the remaining 53 patients (96.36%) had opened surgical treatment. Most of the stones are in the bladder in 29 patients (52%). Twenty-one patients (38.18%) had upper urinary tract stones out of which 13 were in the renal pelvis.Conclusion: Urolithiasis is also common in the developing communities. Despite the changing pattern from lower to the upper tract in developed countries, we found lower tract stone dominating as seen in many underdeveloped. This may be attributable to yet to establish environmental or genetic factors. Link for e-copy: http://www.bornomedicaljournal.com/pdfs/PATTERN OF PRESENTATION AND MANAGEMENT O [...] Pattern of presentation and management of urolithiasis at federal medical centre, Nguru, Nigeria [] / B. M. Abubakar, Author ; A. Abubakar, Author ; I. E. Suleiman, Author ; B. S. Makama, Author ; A. A. Abdulhafeez, Author ; M. G. Gashua, Author . - Maiduguri (1414, Nigeria - Borno State) : Medical and Dental Consultants Association of Nigeria - Nigerian Medical Association, 2017 . - p.63-70, fig., tab. : Journal Article. - (Borno Medical Journal, ISSN 2437-1734; 14(1)) . ISSN : 2437-1734 Languages : English Keywords: Urolithiasis - diagnosis  Urolithiasis - therapy  Disease Management  Retrospective Studies  Nigeria Abstract: Background: Urolithiasis has been with mankind since ancient time. Although it is more common in the developed world, the pattern of presentation in the developing countries is tending towards that of developed countries. Objectives: To evaluate the pattern of presentations and treatments offered to patients with urolithiasis over the last 2 years at Federal Medical Centre (FMC), Nguru.Materials and Methods: The study is a 2-year retrospective review of patients managed for urolithiasis at FMC Nguru. The patients' bio-data, pattern of presentation and radiological features of the stones, as well as the treatment given to the patients, were reviewed.Results: The records of 55 patients were reviewed; the mean age was 24.1 years with a range of 1.5 to 70years. The male to female ratio was 10:1. The most common presenting symptom was painful micturition in 21 patients (38.18%). The total number of stones extracted was 58, one patient had multiple right renal pelvic calculi, another had bilateral renal pelvic stone and the third patient had bladder and distal ureteric stone. Two patients (3.64%) expelled their calculi while awaiting surgery, the remaining 53 patients (96.36%) had opened surgical treatment. Most of the stones are in the bladder in 29 patients (52%). Twenty-one patients (38.18%) had upper urinary tract stones out of which 13 were in the renal pelvis.Conclusion: Urolithiasis is also common in the developing communities. Despite the changing pattern from lower to the upper tract in developed countries, we found lower tract stone dominating as seen in many underdeveloped. This may be attributable to yet to establish environmental or genetic factors. Link for e-copy: http://www.bornomedicaljournal.com/pdfs/PATTERN OF PRESENTATION AND MANAGEMENT O [...]

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Prevalence and outcome of pregnancy among elderly primigravida in Aminu Kano teaching hospital, Kano: a 5 year review / S. A. Ibrahim 

Public ISBD Title : Prevalence and outcome of pregnancy among elderly primigravida in Aminu Kano teaching hospital, Kano: a 5 year review Authors: S. A. Ibrahim, Author ; M. A. Jabbo, Author ; A. R. Attah, Author ; I. D. Garba, Author ; Z. Muhammad, Author Publisher: Maiduguri [Nigeria - Borno State] : Medical and Dental Consultants Association of Nigeria - Nigerian Medical Association Publication Date: 2016 Series: Borno Medical Journal, ISSN 2437-1734 No. 13(1) Pagination: p.9-15, tab. Layout: Journal Article ISSN (or other code): 2437-1734 Languages : English Keywords: Pregnancy Outcome  Gravidity  Obstetric Labor Complications  Premature Birth  Prevalence  Nigeria Abstract: Background: As women increasingly delay child bearing, the proportion of women having their first delivery at ''advanced maternal age'' is expected to rise. These elderly primigravidae have traditionally been considered to be at increased risk of adverse maternal and perinatal outcomes compared to their younger counterparts, because of associated pregnancy and labour complications. Objectives: To determine the prevalence of elderly primigravidae and compare their pregnancy outcome with that of younger primigravidae in Aminu Kano Teaching Hospital, Kano. Materials And Methods: This was a retrospective case control study comparing the pregnancy outcome of primigravid mothers aged 35 years and above (elderly primigravidae) with those of younger primigravidae aged 20-25 years, who delivered at Aminu Kano Teaching Hospital between January 2009 and December 2013. Results: There were 18,452 deliveries during the period under review, out of which 295 were primigravidae aged 35 years or above giving a prevalence of 1.6%. There was statistically significant higher preterm delivery rate ( X2= 10.30, P= 0.001) and caesarean delivery rate (X2= 12.15, P= 0.0001) among the elderly primigravidae compared to younger primigravidae. The elderly primigravidae were more prone to hypertensive disorders in pregnancy (X2=23.96, P=0.0001) and diabetes (X2=4.689, P=0.030) compared to the younger primigravidae. The prevalence of antepartum haemorrhage (X2=6.434, P=0.011) and uterine fibroids (X2=5.549, P=0.019) were also statistically significant among the elderly primigravidae compared to the younger primigravidae. There was no significant difference in the other maternal and foetal outcome measures. Conclusion: The prevalence of elderly primigravidae in this study was 1.6%. The prevalence of obstetric complications such as preterm delivery, antepartum haemorrhage, uterine fibroids coexisting with pregnancy and medical conditions like hypertensive disorders in pregnancy and diabetes mellitus are higher among elderly primigravidae compared to younger primigravidae. The elderly primigravidae were also more liable to have caesarean deliveries than the younger primigravidae. However there was no difference in the fetal outcome in the two groups Link for e-copy: http://www.bornomedicaljournal.com/pdfs/PREVALENCE AND OUTCOME OF PREGNANCY AMON [...] Prevalence and outcome of pregnancy among elderly primigravida in Aminu Kano teaching hospital, Kano: a 5 year review [] / S. A. Ibrahim, Author ; M. A. Jabbo, Author ; A. R. Attah, Author ; I. D. Garba, Author ; Z. Muhammad, Author . - Maiduguri (1414, Nigeria - Borno State) : Medical and Dental Consultants Association of Nigeria - Nigerian Medical Association, 2016 . - p.9-15, tab. : Journal Article. - (Borno Medical Journal, ISSN 2437-1734; 13(1)) . ISSN : 2437-1734 Languages : English Keywords: Pregnancy Outcome  Gravidity  Obstetric Labor Complications  Premature Birth  Prevalence  Nigeria Abstract: Background: As women increasingly delay child bearing, the proportion of women having their first delivery at ''advanced maternal age'' is expected to rise. These elderly primigravidae have traditionally been considered to be at increased risk of adverse maternal and perinatal outcomes compared to their younger counterparts, because of associated pregnancy and labour complications. Objectives: To determine the prevalence of elderly primigravidae and compare their pregnancy outcome with that of younger primigravidae in Aminu Kano Teaching Hospital, Kano. Materials And Methods: This was a retrospective case control study comparing the pregnancy outcome of primigravid mothers aged 35 years and above (elderly primigravidae) with those of younger primigravidae aged 20-25 years, who delivered at Aminu Kano Teaching Hospital between January 2009 and December 2013. Results: There were 18,452 deliveries during the period under review, out of which 295 were primigravidae aged 35 years or above giving a prevalence of 1.6%. There was statistically significant higher preterm delivery rate ( X2= 10.30, P= 0.001) and caesarean delivery rate (X2= 12.15, P= 0.0001) among the elderly primigravidae compared to younger primigravidae. The elderly primigravidae were more prone to hypertensive disorders in pregnancy (X2=23.96, P=0.0001) and diabetes (X2=4.689, P=0.030) compared to the younger primigravidae. The prevalence of antepartum haemorrhage (X2=6.434, P=0.011) and uterine fibroids (X2=5.549, P=0.019) were also statistically significant among the elderly primigravidae compared to the younger primigravidae. There was no significant difference in the other maternal and foetal outcome measures. Conclusion: The prevalence of elderly primigravidae in this study was 1.6%. The prevalence of obstetric complications such as preterm delivery, antepartum haemorrhage, uterine fibroids coexisting with pregnancy and medical conditions like hypertensive disorders in pregnancy and diabetes mellitus are higher among elderly primigravidae compared to younger primigravidae. The elderly primigravidae were also more liable to have caesarean deliveries than the younger primigravidae. However there was no difference in the fetal outcome in the two groups Link for e-copy: http://www.bornomedicaljournal.com/pdfs/PREVALENCE AND OUTCOME OF PREGNANCY AMON [...]

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Review on the use of dexamethasone and its impact on fertility and pregnancy / Dauda Yahi 

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Role of national blood transfusion service (NBTS) in promoting emergency obstetrics care (EMOC) / A. A. Kullima 

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Self-reported hearing-related complaints among dental professionals: a questionnaire-based survey / Ahmed Abdulazeez 

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Seroprevalence of toxoplasma gondii among HIV patients in the University of Benin Teaching Hospital (UBTH), Benin City, Edo State, Nigeria / Edirin O. Yusuf 

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Serum adiponectin levels in pregnant women with gestational diabetes mellitus in Zaria, north west Nigeria: a cross sectional study / Mohammed Abdullahi 

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Serum lipid profiles and atherogenic index in pregnant sahel goats: public health implications / Dauda Yahi 

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A ten year review of female sterilization at the university of Maiduguri teaching hospital, Maiduguri, Nigeria / A. A. Buba 

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Testicular and paratesticular non- neoplastic lesions in university of maiduguri teaching hospital: a 10-year retrospective review / K. Abba 

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Traditional uvulectomy among the neonates: experience in a Nigerian tertiary health institution / M. Abdullahi 

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