Burkitt's lymphoma in Cameroon: a review of 300 cases in two referral health facilities in Yaounde / G. E. Enow-Orock  

Public ISBD Title : Burkitt's lymphoma in Cameroon: a review of 300 cases in two referral health facilities in Yaounde Authors: G. E. Enow-Orock ; B. Tchemtchoua, Author ; N. P. Koki, Author Publisher: Yaounde [Cameroon] : Association of Cancerology and Pathology Publication Date: 2012 Series: African Journal of Pathology and Microbiology, ISSN 2090-9039 No. 1 Pagination: p.1-4, tab. Layout: Journal Article ISSN (or other code): 2090-9039 Languages : English Keywords: Burkitt Lymphoma  Health Facilities  Case Reports - Review  Yaounde - Camerouun Abstract: In this descriptive retrospective study; we reviewed 300 cases of Burkitt's lymphoma (BL) diagnosed within 10 years from January 1; 2000 to December 31; 2010. The study took place in the pathology laboratories of the Central Hospital and the General Hospital in Yaounde; Cameroon. The aim was to review the anatomo-clinical and epidemiological aspects of the disease; especially with respect to its localization. We found that BL affected mostly children aged 5-14 years with peaks at 4 and 12 years. A slight male predominance was observed. The abdomino-pelvic site was more frequent (57.7%). Diagnosis of the tumor was mainly by fine-needle aspiration cytology (FNAC). About 6% of our patients tested positive for the human immunodeficiency virus (HIV). We recommend further in-depth studies to find out if there are any emerging factors that influence the localization of the disease in endemic areas or if our finding is incidental. Link for e-copy: https://pdfs.semanticscholar.org/2f07/97321d79a97f44661021d0d1b0b702b46920.pdf Burkitt's lymphoma in Cameroon: a review of 300 cases in two referral health facilities in Yaounde [] / G. E. Enow-Orock ; B. Tchemtchoua, Author ; N. P. Koki, Author . - Yaounde (Cameroon) : Association of Cancerology and Pathology, 2012 . - p.1-4, tab. : Journal Article. - (African Journal of Pathology and Microbiology, ISSN 2090-9039; 1) . ISSN : 2090-9039 Languages : English Keywords: Burkitt Lymphoma  Health Facilities  Case Reports - Review  Yaounde - Camerouun Abstract: In this descriptive retrospective study; we reviewed 300 cases of Burkitt's lymphoma (BL) diagnosed within 10 years from January 1; 2000 to December 31; 2010. The study took place in the pathology laboratories of the Central Hospital and the General Hospital in Yaounde; Cameroon. The aim was to review the anatomo-clinical and epidemiological aspects of the disease; especially with respect to its localization. We found that BL affected mostly children aged 5-14 years with peaks at 4 and 12 years. A slight male predominance was observed. The abdomino-pelvic site was more frequent (57.7%). Diagnosis of the tumor was mainly by fine-needle aspiration cytology (FNAC). About 6% of our patients tested positive for the human immunodeficiency virus (HIV). We recommend further in-depth studies to find out if there are any emerging factors that influence the localization of the disease in endemic areas or if our finding is incidental. Link for e-copy: https://pdfs.semanticscholar.org/2f07/97321d79a97f44661021d0d1b0b702b46920.pdf

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Caracterisation phénotypique des souches de pseudomonas aeruginosa isolées dans la ville de Yaoundé (Cameroun) / Hortense Gonsu Kamga  

Public ISBD Title : Caracterisation phénotypique des souches de pseudomonas aeruginosa isolées dans la ville de Yaoundé (Cameroun) Authors: Hortense Gonsu Kamga ; Michel Toukam, Author ; Zacharie Sando, Author ; Jean Marie Ndifo Ngamba, Author ; Calixte Didier Mbakop, Author ; Dieudonne Adiogo, Author Publisher: Yaounde [Cameroon] : Association of Cancerology and Pathology Publication Date: 2015 Series: African Journal of Pathology and Microbiology, ISSN 2090-9039 No. 4 Pagination: p.1-4, fig. tab. Layout: Journal Article ISSN (or other code): 2090-9039 Keywords: Pseudomonas aeruginosa  Résistance bactérienne aux médicaments  Phénotype  Infection croisée  Cameroun - Yaoundé Abstract: Introduction. L'objectif etait de determiner la proportion de souches de Pseudomonas aeruginosa (P. aeruginosa) exprimant des mecanismes de resistance dans la ville de Yaounde. Methode. Il s'agissait d'une etude prospective et descriptive realisee du 02 janvier au 30 juin 2012. Des souches de P. aeruginosa provenant de divers produits pathologiques de patients ont ete identifiees a l'aide de la galerie API 20NE (Biomerieux). Pour les prelevements urinaires; une cytologie etait faite pour verifier l'absence de cancer. La lecture interpretative de l'antibiogramme a ete faite par diffusion sur gelose Mueller-Hinton selon CA-SFM 2011. Resultats. Au total 34 souches de P. aeruginosa ont ete isolees dont 85;3?% chez patients hospitalises. Parmi ces souches; 41;2?% etaient isolees des urines; 23;5?% des hemocultures et 17;6?% des suppurations. Les urines montraient a l'examen cytologique des modifications inflammatoires aigues et l'absence de cancer. Le profil de resistance aux antibiotiques a montre une resistance elevee preferentielle des Beta-lactamines notamment a la ticarcilline (35;29?%). Concernant les Beta-lactamines; les phenotypes les plus observes ont ete pour les 2/3 sauvages et 26;5?% pour les penicillinases ; quant aux aminosides 94;1?% etaient de phenotype sauvage; tandis que 2/3 etaient de type sauvage pour les fluoroquinolones. Conclusion. Une association Beta-lactamines/aminosides ou Beta-lactamines/fluoroquinolones pourrait etre preconisee afin de lutter contre toute infection a P. aeruginosa. Link for e-copy: https://www.researchgate.net/publication/281433874_ Caracterisation phénotypique des souches de pseudomonas aeruginosa isolées dans la ville de Yaoundé (Cameroun) [] / Hortense Gonsu Kamga ; Michel Toukam, Author ; Zacharie Sando, Author ; Jean Marie Ndifo Ngamba, Author ; Calixte Didier Mbakop, Author ; Dieudonne Adiogo, Author . - Yaounde (Cameroon) : Association of Cancerology and Pathology, 2015 . - p.1-4, fig. tab. : Journal Article. - (African Journal of Pathology and Microbiology, ISSN 2090-9039; 4) . ISSN : 2090-9039 Keywords: Pseudomonas aeruginosa  Résistance bactérienne aux médicaments  Phénotype  Infection croisée  Cameroun - Yaoundé Abstract: Introduction. L'objectif etait de determiner la proportion de souches de Pseudomonas aeruginosa (P. aeruginosa) exprimant des mecanismes de resistance dans la ville de Yaounde. Methode. Il s'agissait d'une etude prospective et descriptive realisee du 02 janvier au 30 juin 2012. Des souches de P. aeruginosa provenant de divers produits pathologiques de patients ont ete identifiees a l'aide de la galerie API 20NE (Biomerieux). Pour les prelevements urinaires; une cytologie etait faite pour verifier l'absence de cancer. La lecture interpretative de l'antibiogramme a ete faite par diffusion sur gelose Mueller-Hinton selon CA-SFM 2011. Resultats. Au total 34 souches de P. aeruginosa ont ete isolees dont 85;3?% chez patients hospitalises. Parmi ces souches; 41;2?% etaient isolees des urines; 23;5?% des hemocultures et 17;6?% des suppurations. Les urines montraient a l'examen cytologique des modifications inflammatoires aigues et l'absence de cancer. Le profil de resistance aux antibiotiques a montre une resistance elevee preferentielle des Beta-lactamines notamment a la ticarcilline (35;29?%). Concernant les Beta-lactamines; les phenotypes les plus observes ont ete pour les 2/3 sauvages et 26;5?% pour les penicillinases ; quant aux aminosides 94;1?% etaient de phenotype sauvage; tandis que 2/3 etaient de type sauvage pour les fluoroquinolones. Conclusion. Une association Beta-lactamines/aminosides ou Beta-lactamines/fluoroquinolones pourrait etre preconisee afin de lutter contre toute infection a P. aeruginosa. Link for e-copy: https://www.researchgate.net/publication/281433874_

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Clinical and Therapeutic Features of Neurofibromatosis in Ghana / Emmanuel J. K. Adu  

Public ISBD Title : Clinical and Therapeutic Features of Neurofibromatosis in Ghana Authors: Emmanuel J. K. Adu ; Adofo Koranteng, Author Publisher: Yaounde [Cameroon] : Association of Cancerology and Pathology Publication Date: 2014 Series: African Journal of Pathology and Microbiology, ISSN 2090-9039 Pagination: p.1-5, fig., tab. Layout: Journal Article ISSN (or other code): 2090-9039 Languages : English Keywords: Neurofibromatoses - epidemiology  Neurofibromatoses - diagnosis  Neurofibromatoses - therapy  Neurilemmoma  Ghana - Kumasi Abstract: Introduction. Neurofibromatosis (NF) is a generalized form of benign tumors of the peripheral nerves involving the skin; subcutaneous tissue; and bone. It comprises neurofibromatosis type 1 (NF-1); neurofibromatosis type 2 (NF-2); and schwannomatosis. Objective. To document the clinical and epidemiological features of patients with NF presenting at Komfo Anokye Teaching Hospital (KATH) in Kumasi; Ghana; from January 2009 to December 2013; and the outcome of management. Patients and methods. This is a retrospective study. Data on all patients managed within the study period were retrieved from the records of the surgical outpatient department (SOPD) of KATH and theater records and analyzed. Results. Fifteen patients underwent surgery for function impairing and disfiguring lesions; comprising five males and 10 females. Their ages ranged from three years to 55 years; with a mean age of 27.3 years. Seventeen lesions were found on the 15 patients that required surgery: 10 on the head and neck; three on the trunk; two on the upper limbs; and two on the lower limbs. Three of the lesions were neurofibromas; 14 were plexiform lesions. Fourteen patients had NF-1; only one patient had NF-2; there were no cases of schwannomatosis. Debulking was done for 12 patients; this was combined with suspension in two cases and enucleation in one case. Excision was done for five patients. Eight of the lesions recurred and the patients underwent a second debulking procedure. Conclusion. NF causes disfigurement and functional deficits in affected patients. Surgery can achieve symptomatic relief. Early presentation is recommended for optimal results. Link for e-copy: http://www.oakhillspub.com/index.php/ajpm/article/view/138/121 Clinical and Therapeutic Features of Neurofibromatosis in Ghana [] / Emmanuel J. K. Adu ; Adofo Koranteng, Author . - Yaounde (Cameroon) : Association of Cancerology and Pathology, 2014 . - p.1-5, fig., tab. : Journal Article. - (African Journal of Pathology and Microbiology, ISSN 2090-9039) . ISSN : 2090-9039 Languages : English Keywords: Neurofibromatoses - epidemiology  Neurofibromatoses - diagnosis  Neurofibromatoses - therapy  Neurilemmoma  Ghana - Kumasi Abstract: Introduction. Neurofibromatosis (NF) is a generalized form of benign tumors of the peripheral nerves involving the skin; subcutaneous tissue; and bone. It comprises neurofibromatosis type 1 (NF-1); neurofibromatosis type 2 (NF-2); and schwannomatosis. Objective. To document the clinical and epidemiological features of patients with NF presenting at Komfo Anokye Teaching Hospital (KATH) in Kumasi; Ghana; from January 2009 to December 2013; and the outcome of management. Patients and methods. This is a retrospective study. Data on all patients managed within the study period were retrieved from the records of the surgical outpatient department (SOPD) of KATH and theater records and analyzed. Results. Fifteen patients underwent surgery for function impairing and disfiguring lesions; comprising five males and 10 females. Their ages ranged from three years to 55 years; with a mean age of 27.3 years. Seventeen lesions were found on the 15 patients that required surgery: 10 on the head and neck; three on the trunk; two on the upper limbs; and two on the lower limbs. Three of the lesions were neurofibromas; 14 were plexiform lesions. Fourteen patients had NF-1; only one patient had NF-2; there were no cases of schwannomatosis. Debulking was done for 12 patients; this was combined with suspension in two cases and enucleation in one case. Excision was done for five patients. Eight of the lesions recurred and the patients underwent a second debulking procedure. Conclusion. NF causes disfigurement and functional deficits in affected patients. Surgery can achieve symptomatic relief. Early presentation is recommended for optimal results. Link for e-copy: http://www.oakhillspub.com/index.php/ajpm/article/view/138/121

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Cornual molar ectopic pregnancy: a case report with difficult management in poor resources settings / Bruno Kenfack  

Public ISBD Title : Cornual molar ectopic pregnancy: a case report with difficult management in poor resources settings Authors: Bruno Kenfack ; Zacharie Sando, Author ; Grace Nganwa, Author ; Ambe Gilbert Che, Author ; Philip Njotan Nana, Author ; Emile Mboudou, Author Publisher: Yaounde [Cameroon] : Association of Cancerology and Pathology Publication Date: 2012 Series: African Journal of Pathology and Microbiology, ISSN 2090-9039 No. 1 Pagination: p.1-3, fig. Layout: Journal Article ISSN (or other code): 2090-9039 Languages : English Keywords: Pregnancy Cornual  diagnosis  Gestational Age  Disease Management  Case Reports Abstract: Molar pregnancy is a rare entity and ectopic location of pregnancy in the uterine horn represents the least frequent site of implantation. This paper presents a rare case of molar cornual ectopic pregnancy at advanced gestational age with a particular difficulty in diagnosis and management. A 35-year-old woman; gravida 4 para 3 with a history of 12 weeks amenorrhea; was operated for presumed ruptured ectopic pregnancy. Per-operative findings showed swollen villi in clusters that looked like bunches of grapes; characteristic of a complete hydatiform mole; located at the left horn of the uterus. Histopathologic examination confirmed the diagnosis. Bleeding could not be controlled with suturing and hysterectomy was eventually done. Although rare; molar pregnancy can be ectopic. If it is located at the uterine horn; bleeding may be difficult to control if at a gestational age of 12 weeks or more. Link for e-copy: https://www.researchgate.net/publication/276219297 Cornual molar ectopic pregnancy: a case report with difficult management in poor resources settings [] / Bruno Kenfack ; Zacharie Sando, Author ; Grace Nganwa, Author ; Ambe Gilbert Che, Author ; Philip Njotan Nana, Author ; Emile Mboudou, Author . - Yaounde (Cameroon) : Association of Cancerology and Pathology, 2012 . - p.1-3, fig. : Journal Article. - (African Journal of Pathology and Microbiology, ISSN 2090-9039; 1) . ISSN : 2090-9039 Languages : English Keywords: Pregnancy Cornual  diagnosis  Gestational Age  Disease Management  Case Reports Abstract: Molar pregnancy is a rare entity and ectopic location of pregnancy in the uterine horn represents the least frequent site of implantation. This paper presents a rare case of molar cornual ectopic pregnancy at advanced gestational age with a particular difficulty in diagnosis and management. A 35-year-old woman; gravida 4 para 3 with a history of 12 weeks amenorrhea; was operated for presumed ruptured ectopic pregnancy. Per-operative findings showed swollen villi in clusters that looked like bunches of grapes; characteristic of a complete hydatiform mole; located at the left horn of the uterus. Histopathologic examination confirmed the diagnosis. Bleeding could not be controlled with suturing and hysterectomy was eventually done. Although rare; molar pregnancy can be ectopic. If it is located at the uterine horn; bleeding may be difficult to control if at a gestational age of 12 weeks or more. Link for e-copy: https://www.researchgate.net/publication/276219297

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Helicobacter pylori cagA Gene in Egyptian sewage workers / Salah Agha  

Public ISBD Title : Helicobacter pylori cagA Gene in Egyptian sewage workers Authors: Salah Agha ; Mona F. Foad, Author ; Nabil J. Awadalla, Author ; Niveen Saudy, Author Publisher: Yaounde [Cameroon] : Association of Cancerology and Pathology Publication Date: 2013 Series: African Journal of Pathology and Microbiology, ISSN 2090-9039 No. 2 Pagination: p.1-6, tab. Layout: Journal Article ISSN (or other code): 2090-9039 Languages : English Keywords: Caga protein  Helicobacter pylori - Helicobacter pylori  Sewage  Occupational Exposure  Egypt Abstract: A comparative cross-sectional study was conducted on 60 sewage workers and 30 matched unexposed referents from Mansoura city; Egypt; to estimate the prevalence and risk factors of Helicobacter pylori (H. pylori). Stool culture and detection of H. pylori antigen were done. In addition; the polymerase chain reaction (PCR) amplification of cytotoxin-associated gene A (cagA) gene in H. pylori in stool samples was carried out. The prevalence of H. pylori in sewage workers was 56.7% compared to 16.7% in the comparison group with a highly statistically significant difference between both groups. H. pylori cagA gene was present in 64.7% of H. pylori-infected sewage workers compared with 40% of controls. cagA gene was associated with more dyspeptic symptoms (77.3%) in infected workers compared to those of noninfected ones (33.3%) (P = .041). The risk of H. pylori was significantly higher among workers with poor compliance with personal protective equipment (PPE) (OR = 3.00); with duration of work 20 years (OR = 4.71); older than 45 years (OR = 4.27); and of low education level (OR = 11.2). We concluded that H. pylori infection and heartburn with or without epigastric pain are significant health problems in the studied sewage workers. Low education and poor compliance with PPE were the only predictors of H. pylori infection in sewage workers. Link for e-copy: https://pdfs.semanticscholar.org/a685/9fd18b13dc17be51a2f866c1836e2b3026e9.pdf?_ [...] Helicobacter pylori cagA Gene in Egyptian sewage workers [] / Salah Agha ; Mona F. Foad, Author ; Nabil J. Awadalla, Author ; Niveen Saudy, Author . - Yaounde (Cameroon) : Association of Cancerology and Pathology, 2013 . - p.1-6, tab. : Journal Article. - (African Journal of Pathology and Microbiology, ISSN 2090-9039; 2) . ISSN : 2090-9039 Languages : English Keywords: Caga protein  Helicobacter pylori - Helicobacter pylori  Sewage  Occupational Exposure  Egypt Abstract: A comparative cross-sectional study was conducted on 60 sewage workers and 30 matched unexposed referents from Mansoura city; Egypt; to estimate the prevalence and risk factors of Helicobacter pylori (H. pylori). Stool culture and detection of H. pylori antigen were done. In addition; the polymerase chain reaction (PCR) amplification of cytotoxin-associated gene A (cagA) gene in H. pylori in stool samples was carried out. The prevalence of H. pylori in sewage workers was 56.7% compared to 16.7% in the comparison group with a highly statistically significant difference between both groups. H. pylori cagA gene was present in 64.7% of H. pylori-infected sewage workers compared with 40% of controls. cagA gene was associated with more dyspeptic symptoms (77.3%) in infected workers compared to those of noninfected ones (33.3%) (P = .041). The risk of H. pylori was significantly higher among workers with poor compliance with personal protective equipment (PPE) (OR = 3.00); with duration of work 20 years (OR = 4.71); older than 45 years (OR = 4.27); and of low education level (OR = 11.2). We concluded that H. pylori infection and heartburn with or without epigastric pain are significant health problems in the studied sewage workers. Low education and poor compliance with PPE were the only predictors of H. pylori infection in sewage workers. Link for e-copy: https://pdfs.semanticscholar.org/a685/9fd18b13dc17be51a2f866c1836e2b3026e9.pdf?_ [...]

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Importance of bacterial resistance in streptococcus pneumoniae and streptococcus pyogenes in the center region in Cameroon / Dieudonne Adiogo 

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Indications et aspects histopathologiques des biopsies de l'endometre a l'Hopital Gyneco-Obstetrique et Pediatrique de Yaoundé (Cameroun) / Zacharie Sando  

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Intra- and interobserver reproducibility of grading of helicobacter pylori gastritis according to the updated sydney system / Zacharie Sando  

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Les modifications morphologiques placentaires observees chez le nouveau ne hypotrophique Camerounais / Amadou Fewou 

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Phénotypes de résistance des souches d'escherichia coli responsables des infections urinaires communautaires dans la ville de Yaoundé (Cameroun) / H. Gonsu Kamga  

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Positive tumor margins in wide local excision of breast cancer: a 10-year retrospective study / E. M. Der  

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Reproductibilite interobservateurs des scores de Knodell et Metavir en milieu Camerounais pour les hepatites virales chroniques / Carole-Marlyse Menzy-Ndjole  

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Susceptibility to colistin of multi-resistant pseudomonas aeruginosa isolated in Douala Laquintinie Hospital, Cameroon / Noel Simon Ateba  

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The Susceptibility Pattern of Salmonella Species to Commonly Used Antibiotics in the Bamenda District Health Area; Cameroon / Nkeza Awung  

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Triple-negative breast cancer among ghanaian women seen at Korle-Bu teaching hospital / E. M. Der  

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