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Title : | Caracterisation phénotypique des souches de pseudomonas aeruginosa isolées dans la ville de Yaoundé (Cameroun) | Authors: | Hortense Gonsu Kamga ; Michel Toukam, Author ; Zacharie Sando, Author ; Jean Marie Ndifo Ngamba, Author ; Calixte Didier Mbakop, Author ; Dieudonne Adiogo, Author | Publisher: | Yaounde [Cameroon] : Association of Cancerology and Pathology | Publication Date: | 2015 | Series: | African Journal of Pathology and Microbiology, ISSN 2090-9039 No. 4 | Pagination: | p.1-4, fig. tab. | Layout: | Journal Article | ISSN (or other code): | 2090-9039 | Keywords: | Pseudomonas aeruginosa Résistance bactérienne aux médicaments Phénotype Infection croisée Cameroun - Yaoundé | Abstract: | Introduction. L'objectif etait de determiner la proportion de souches de Pseudomonas aeruginosa (P. aeruginosa) exprimant des mecanismes de resistance dans la ville de Yaounde. Methode. Il s'agissait d'une etude prospective et descriptive realisee du 02 janvier au 30 juin 2012. Des souches de P. aeruginosa provenant de divers produits pathologiques de patients ont ete identifiees a l'aide de la galerie API 20NE (Biomerieux). Pour les prelevements urinaires; une cytologie etait faite pour verifier l'absence de cancer. La lecture interpretative de l'antibiogramme a ete faite par diffusion sur gelose Mueller-Hinton selon CA-SFM 2011. Resultats. Au total 34 souches de P. aeruginosa ont ete isolees dont 85;3?% chez patients hospitalises. Parmi ces souches; 41;2?% etaient isolees des urines; 23;5?% des hemocultures et 17;6?% des suppurations. Les urines montraient a l'examen cytologique des modifications inflammatoires aigues et l'absence de cancer. Le profil de resistance aux antibiotiques a montre une resistance elevee preferentielle des Beta-lactamines notamment a la ticarcilline (35;29?%). Concernant les Beta-lactamines; les phenotypes les plus observes ont ete pour les 2/3 sauvages et 26;5?% pour les penicillinases ; quant aux aminosides 94;1?% etaient de phenotype sauvage; tandis que 2/3 etaient de type sauvage pour les fluoroquinolones. Conclusion. Une association Beta-lactamines/aminosides ou Beta-lactamines/fluoroquinolones pourrait etre preconisee afin de lutter contre toute infection a P. aeruginosa. | Link for e-copy: | https://www.researchgate.net/publication/281433874_ |
Caracterisation phénotypique des souches de pseudomonas aeruginosa isolées dans la ville de Yaoundé (Cameroun) [] / Hortense Gonsu Kamga ; Michel Toukam, Author ; Zacharie Sando, Author ; Jean Marie Ndifo Ngamba, Author ; Calixte Didier Mbakop, Author ; Dieudonne Adiogo, Author . - Yaounde (Cameroon) : Association of Cancerology and Pathology, 2015 . - p.1-4, fig. tab. : Journal Article. - ( African Journal of Pathology and Microbiology, ISSN 2090-9039; 4) . ISSN : 2090-9039 Keywords: | Pseudomonas aeruginosa Résistance bactérienne aux médicaments Phénotype Infection croisée Cameroun - Yaoundé | Abstract: | Introduction. L'objectif etait de determiner la proportion de souches de Pseudomonas aeruginosa (P. aeruginosa) exprimant des mecanismes de resistance dans la ville de Yaounde. Methode. Il s'agissait d'une etude prospective et descriptive realisee du 02 janvier au 30 juin 2012. Des souches de P. aeruginosa provenant de divers produits pathologiques de patients ont ete identifiees a l'aide de la galerie API 20NE (Biomerieux). Pour les prelevements urinaires; une cytologie etait faite pour verifier l'absence de cancer. La lecture interpretative de l'antibiogramme a ete faite par diffusion sur gelose Mueller-Hinton selon CA-SFM 2011. Resultats. Au total 34 souches de P. aeruginosa ont ete isolees dont 85;3?% chez patients hospitalises. Parmi ces souches; 41;2?% etaient isolees des urines; 23;5?% des hemocultures et 17;6?% des suppurations. Les urines montraient a l'examen cytologique des modifications inflammatoires aigues et l'absence de cancer. Le profil de resistance aux antibiotiques a montre une resistance elevee preferentielle des Beta-lactamines notamment a la ticarcilline (35;29?%). Concernant les Beta-lactamines; les phenotypes les plus observes ont ete pour les 2/3 sauvages et 26;5?% pour les penicillinases ; quant aux aminosides 94;1?% etaient de phenotype sauvage; tandis que 2/3 etaient de type sauvage pour les fluoroquinolones. Conclusion. Une association Beta-lactamines/aminosides ou Beta-lactamines/fluoroquinolones pourrait etre preconisee afin de lutter contre toute infection a P. aeruginosa. | Link for e-copy: | https://www.researchgate.net/publication/281433874_ |
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Title : | Clinical and Therapeutic Features of Neurofibromatosis in Ghana | Authors: | Emmanuel J. K. Adu ; Adofo Koranteng, Author | Publisher: | Yaounde [Cameroon] : Association of Cancerology and Pathology | Publication Date: | 2014 | Series: | African Journal of Pathology and Microbiology, ISSN 2090-9039 | Pagination: | p.1-5, fig., tab. | Layout: | Journal Article | ISSN (or other code): | 2090-9039 | Languages : | English | Keywords: | Neurofibromatoses - epidemiology Neurofibromatoses - diagnosis Neurofibromatoses - therapy Neurilemmoma Ghana - Kumasi | Abstract: | Introduction. Neurofibromatosis (NF) is a generalized form of benign tumors of the peripheral nerves involving the skin; subcutaneous tissue; and bone. It comprises neurofibromatosis type 1 (NF-1); neurofibromatosis type 2 (NF-2); and schwannomatosis. Objective. To document the clinical and epidemiological features of patients with NF presenting at Komfo Anokye Teaching Hospital (KATH) in Kumasi; Ghana; from January 2009 to December 2013; and the outcome of management. Patients and methods. This is a retrospective study. Data on all patients managed within the study period were retrieved from the records of the surgical outpatient department (SOPD) of KATH and theater records and analyzed. Results. Fifteen patients underwent surgery for function impairing and disfiguring lesions; comprising five males and 10 females. Their ages ranged from three years to 55 years; with a mean age of 27.3 years. Seventeen lesions were found on the 15 patients that required surgery: 10 on the head and neck; three on the trunk; two on the upper limbs; and two on the lower limbs. Three of the lesions were neurofibromas; 14 were plexiform lesions. Fourteen patients had NF-1; only one patient had NF-2; there were no cases of schwannomatosis. Debulking was done for 12 patients; this was combined with suspension in two cases and enucleation in one case. Excision was done for five patients. Eight of the lesions recurred and the patients underwent a second debulking procedure. Conclusion. NF causes disfigurement and functional deficits in affected patients. Surgery can achieve symptomatic relief. Early presentation is recommended for optimal results. | Link for e-copy: | http://www.oakhillspub.com/index.php/ajpm/article/view/138/121 |
Clinical and Therapeutic Features of Neurofibromatosis in Ghana [] / Emmanuel J. K. Adu ; Adofo Koranteng, Author . - Yaounde (Cameroon) : Association of Cancerology and Pathology, 2014 . - p.1-5, fig., tab. : Journal Article. - ( African Journal of Pathology and Microbiology, ISSN 2090-9039) . ISSN : 2090-9039 Languages : English Keywords: | Neurofibromatoses - epidemiology Neurofibromatoses - diagnosis Neurofibromatoses - therapy Neurilemmoma Ghana - Kumasi | Abstract: | Introduction. Neurofibromatosis (NF) is a generalized form of benign tumors of the peripheral nerves involving the skin; subcutaneous tissue; and bone. It comprises neurofibromatosis type 1 (NF-1); neurofibromatosis type 2 (NF-2); and schwannomatosis. Objective. To document the clinical and epidemiological features of patients with NF presenting at Komfo Anokye Teaching Hospital (KATH) in Kumasi; Ghana; from January 2009 to December 2013; and the outcome of management. Patients and methods. This is a retrospective study. Data on all patients managed within the study period were retrieved from the records of the surgical outpatient department (SOPD) of KATH and theater records and analyzed. Results. Fifteen patients underwent surgery for function impairing and disfiguring lesions; comprising five males and 10 females. Their ages ranged from three years to 55 years; with a mean age of 27.3 years. Seventeen lesions were found on the 15 patients that required surgery: 10 on the head and neck; three on the trunk; two on the upper limbs; and two on the lower limbs. Three of the lesions were neurofibromas; 14 were plexiform lesions. Fourteen patients had NF-1; only one patient had NF-2; there were no cases of schwannomatosis. Debulking was done for 12 patients; this was combined with suspension in two cases and enucleation in one case. Excision was done for five patients. Eight of the lesions recurred and the patients underwent a second debulking procedure. Conclusion. NF causes disfigurement and functional deficits in affected patients. Surgery can achieve symptomatic relief. Early presentation is recommended for optimal results. | Link for e-copy: | http://www.oakhillspub.com/index.php/ajpm/article/view/138/121 |
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Title : | Helicobacter pylori cagA Gene in Egyptian sewage workers | Authors: | Salah Agha ; Mona F. Foad, Author ; Nabil J. Awadalla, Author ; Niveen Saudy, Author | Publisher: | Yaounde [Cameroon] : Association of Cancerology and Pathology | Publication Date: | 2013 | Series: | African Journal of Pathology and Microbiology, ISSN 2090-9039 No. 2 | Pagination: | p.1-6, tab. | Layout: | Journal Article | ISSN (or other code): | 2090-9039 | Languages : | English | Keywords: | Caga protein Helicobacter pylori - Helicobacter pylori Sewage Occupational Exposure Egypt | Abstract: | A comparative cross-sectional study was conducted on 60 sewage workers and 30 matched unexposed referents from Mansoura city; Egypt; to estimate the prevalence and risk factors of Helicobacter pylori (H. pylori). Stool culture and detection of H. pylori antigen were done. In addition; the polymerase chain reaction (PCR) amplification of cytotoxin-associated gene A (cagA) gene in H. pylori in stool samples was carried out. The prevalence of H. pylori in sewage workers was 56.7% compared to 16.7% in the comparison group with a highly statistically significant difference between both groups. H. pylori cagA gene was present in 64.7% of H. pylori-infected sewage workers compared with 40% of controls. cagA gene was associated with more dyspeptic symptoms (77.3%) in infected workers compared to those of noninfected ones (33.3%) (P = .041). The risk of H. pylori was significantly higher among workers with poor compliance with personal protective equipment (PPE) (OR = 3.00); with duration of work 20 years (OR = 4.71); older than 45 years (OR = 4.27); and of low education level (OR = 11.2). We concluded that H. pylori infection and heartburn with or without epigastric pain are significant health problems in the studied sewage workers. Low education and poor compliance with PPE were the only predictors of H. pylori infection in sewage workers. | Link for e-copy: | https://pdfs.semanticscholar.org/a685/9fd18b13dc17be51a2f866c1836e2b3026e9.pdf?_ [...] |
Helicobacter pylori cagA Gene in Egyptian sewage workers [] / Salah Agha ; Mona F. Foad, Author ; Nabil J. Awadalla, Author ; Niveen Saudy, Author . - Yaounde (Cameroon) : Association of Cancerology and Pathology, 2013 . - p.1-6, tab. : Journal Article. - ( African Journal of Pathology and Microbiology, ISSN 2090-9039; 2) . ISSN : 2090-9039 Languages : English Keywords: | Caga protein Helicobacter pylori - Helicobacter pylori Sewage Occupational Exposure Egypt | Abstract: | A comparative cross-sectional study was conducted on 60 sewage workers and 30 matched unexposed referents from Mansoura city; Egypt; to estimate the prevalence and risk factors of Helicobacter pylori (H. pylori). Stool culture and detection of H. pylori antigen were done. In addition; the polymerase chain reaction (PCR) amplification of cytotoxin-associated gene A (cagA) gene in H. pylori in stool samples was carried out. The prevalence of H. pylori in sewage workers was 56.7% compared to 16.7% in the comparison group with a highly statistically significant difference between both groups. H. pylori cagA gene was present in 64.7% of H. pylori-infected sewage workers compared with 40% of controls. cagA gene was associated with more dyspeptic symptoms (77.3%) in infected workers compared to those of noninfected ones (33.3%) (P = .041). The risk of H. pylori was significantly higher among workers with poor compliance with personal protective equipment (PPE) (OR = 3.00); with duration of work 20 years (OR = 4.71); older than 45 years (OR = 4.27); and of low education level (OR = 11.2). We concluded that H. pylori infection and heartburn with or without epigastric pain are significant health problems in the studied sewage workers. Low education and poor compliance with PPE were the only predictors of H. pylori infection in sewage workers. | Link for e-copy: | https://pdfs.semanticscholar.org/a685/9fd18b13dc17be51a2f866c1836e2b3026e9.pdf?_ [...] |
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